ATAD2 and BCAR3

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		ATAD2	BCAR3
Description		ATPase family AAA domain containing 2	BCAR3 adaptor protein, NSP family member
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Extracellular Exosome	Cytoplasm Focal Adhesion Membrane Anchoring Junction
	Molecular Function	Nucleotide Binding Chromatin Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Histone Binding	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding
	Biological Process	Nucleosome Assembly Nucleosome Disassembly Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription	Lens Morphogenesis In Camera-type Eye Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Small GTPase-mediated Signal Transduction Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Endothelin Receptor Signaling Pathway
Pathways		TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
Drugs
Diseases
GWAS			Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		12 interacting genes: BAG4 BCAR3 CASP8 E2F1 E2F2 E2F3 E2F4 ESR1 H3-4 H4C14 MYC NCOA3	38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 DRC4 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45
Entrez ID		29028	8412
HPRD ID		10678	05268
Ensembl ID		ENSG00000156802	ENSG00000137936
Uniprot IDs		Q6PL18	A0A384MTS3 B3KNL6 B3KP06 O75815
PDB IDs		3DAI 4QSP 4QSQ 4QSR 4QSS 4QST 4QSU 4QSV 4QSW 4QSX 4QUT 4QUU 4TT2 4TT4 4TT6 4TTE 4TU4 4TU6 4TYL 4TZ2 4TZ8 5A5N 5A5O 5A5P 5A5Q 5A5R 5A81 5A82 5A83 5EPB 5F36 5F3A 5LJ0 5QXI 5QXJ 5QXK 5QXL 5QXM 5QXN 5QXO 5QXP 5QXQ 5QXR 5QXS 5QXT 5QXU 5QXV 5QXW 5QXX 5QXY 5QXZ 5QY0 5R4E 5R4F 5R4V 5R4W 5R4X 5R4Y 5R4Z 6CPS 6EPJ 6EPR 6EPS 6EPT 6EPU 6EPV 6EPW 6EPX 6HDN 6HDO 6HI3 6HI4 6HI5 6HI6 6HI7 6HI8 6HIA 6HIB 6HIC 6HID 6HIE 6S55 6S56 6S57 6YB4 7M98 7PPX 7PX5 7Q6T 7Q6U 7Q6V 7Q6W 7QU7 7QUK 7QUM 7QWO 7QX1 7QXT 7QYK 7QYL 7QZM 7QZY 7QZZ 7R00 7R05 7R0Y 7Z9H 7Z9I 7Z9J 7Z9N 7Z9O 7Z9S 7Z9U 8H3H 8JUW 8JUY 8JUZ 8RU5 8SDO 8SDQ	3T6A
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Cis-regulatory Region Sequence-specific DNA Binding Transcription Regulator Complex DNA-binding Transcription Activator Activity RNA Polymerase II Transcription Regulator Complex Chromatin DNA-binding Transcription Factor Activity Lens Fiber Cell Apoptotic Process Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Protein-containing Complex Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Regulation Of Fibroblast Proliferation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Developmental Process Chromatin Remodeling Apoptotic Signaling Pathway Response To Estradiol Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromatin Organization Regulation Of Apoptotic Process Regulation Of Multicellular Organismal Development Nucleoplasm Nucleobase-containing Compound Biosynthetic Process Sequence-specific DNA Binding Intrinsic Apoptotic Signaling Pathway Regulation Of Programmed Cell Death Positive Regulation Of Cell Population Proliferation Protein-DNA Complex Assembly Cellular Response To Estradiol Stimulus Positive Regulation Of Macromolecule Metabolic Process Regulation Of Smooth Muscle Cell Apoptotic Process Regulation Of Cell Differentiation Positive Regulation Of Apoptotic Process Transcription Coregulator Binding Regulation Of Myeloid Cell Differentiation Positive Regulation Of Programmed Cell Death Regulation Of Cell Population Proliferation Epithelial Cell Apoptotic Process	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity ERBB2 Signaling Pathway Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Basal Plasma Membrane Protein Tyrosine Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Epithelial Cell Proliferation Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Epithelial Cell Proliferation ERBB3:ERBB2 Complex Response To Epidermal Growth Factor Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Regulation Of Cell Population Proliferation Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Epithelial Cell Proliferation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Molecular Function Inhibitor Activity Positive Regulation Of Phosphate Metabolic Process Response To Growth Factor Regulation Of Protein Modification Process Protein Kinase Activity Positive Regulation Of Lymphocyte Migration Positive Chemotaxis ERBB2-EGFR Signaling Pathway Growth Factor Binding Regulation Of Primary Metabolic Process Cell Population Proliferation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Basolateral Plasma Membrane Positive Regulation Of Cell Migration Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway
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