BCAR3 and PSMC3IP

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		BCAR3	PSMC3IP
Description		BCAR3 adaptor protein, NSP family member	PSMC3 interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Focal Adhesion Membrane Anchoring Junction	Condensed Nuclear Chromosome Nucleus Nucleoplasm DNA Recombinase Auxiliary Factor Complex
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	DNA Binding Double-stranded DNA Binding Transcription Coactivator Activity Protein Binding Recombinase Activator Activity
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Small GTPase-mediated Signal Transduction Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Endothelin Receptor Signaling Pathway	Meiotic Joint Molecule Formation DNA Recombination Homologous Chromosome Pairing At Meiosis Reciprocal Meiotic Recombination Meiotic Strand Invasion Involved In Reciprocal Meiotic Recombination Positive Regulation Of DNA-templated Transcription Meiotic Cell Cycle
Pathways			Meiotic recombination
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)	Colorectal or endometrial cancer ( 26621817) White blood cell count ( 32888494)
Interacting Genes		38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 DRC4 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45	20 interacting genes: AR AURKA BCAR3 BRMS1 CASP8 CHEK2 ERBB2 ESR1 ESR2 FGFR4 FZR1 NOTCH2 NR3C1 PIK3CA PSMC3 RB1CC1 RXRA TGFB1 THRB XRCC3
Entrez ID		8412	29893
HPRD ID		05268	16362
Ensembl ID		ENSG00000137936	ENSG00000131470
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	A0A158RUX1 K7ERB6 Q9P2W1
PDB IDs		3T6A
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity ERBB2 Signaling Pathway Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Basal Plasma Membrane Protein Tyrosine Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Epithelial Cell Proliferation Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Epithelial Cell Proliferation ERBB3:ERBB2 Complex Response To Epidermal Growth Factor Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Regulation Of Cell Population Proliferation Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Epithelial Cell Proliferation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Molecular Function Inhibitor Activity Positive Regulation Of Phosphate Metabolic Process Response To Growth Factor Regulation Of Protein Modification Process Protein Kinase Activity Positive Regulation Of Lymphocyte Migration Positive Chemotaxis ERBB2-EGFR Signaling Pathway Growth Factor Binding Regulation Of Primary Metabolic Process Cell Population Proliferation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Basolateral Plasma Membrane Positive Regulation Of Cell Migration Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway	Nuclear Receptor Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Estrogen Response Element Binding Positive Regulation Of Metabolic Process Nuclear Receptor-mediated Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Nuclear Steroid Receptor Activity Hormone-mediated Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Apoptotic Process Positive Regulation Of Signal Transduction Regulation Of MiRNA Transcription Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Cell Death Programmed Cell Death Steroid Binding Regulation Of MiRNA Metabolic Process Positive Regulation Of Cell Communication Intracellular Signal Transduction Positive Regulation Of Signaling Response To Lipid Liver Development Intracellular Receptor Signaling Pathway Enzyme Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Population Proliferation Signal Transduction Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of DNA-templated Transcription Positive Regulation Of MiRNA Transcription Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gland Development Myeloid Leukocyte Differentiation Positive Regulation Of Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Animal Organ Development Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Cellular Response To Hormone Stimulus Positive Regulation Of Protein Metabolic Process
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