ATAD2 and E2F2

Number of citations of the paper that reports this interaction (PMID 20855524)
12

Data Source:
BioGRID (pull down)

		ATAD2	E2F2
Gene Name		ATPase family, AAA domain containing 2	E2F transcription factor 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Extracellular Vesicular Exosome	Nucleoplasm Transcription Factor Complex
	Molecular Function	ATP Binding ATPase Activity	Core Promoter Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Lens Fiber Cell Apoptotic Process
Pathways			DNA Replication Pre-Initiation Cellular Senescence G1 Phase M/G1 Transition Regulation of DNA replication CDC6 association with the ORC:origin complex Oncogene Induced Senescence Cell Cycle, Mitotic Assembly of the pre-replicative complex Cyclin D associated events in G1 Oxidative Stress Induced Senescence Association of licensing factors with the pre-replicative complex Mitotic G1-G1/S phases
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: E2F1 E2F2 E2F3 E2F4 ESR1 HIST2H4A HIST3H3 MYC NCOA3	17 interactors: ARID3A ATAD2 BCAR1 BRD2 CDK3 FHL2 GIT2 GNB5 RB1 RNF144A RYBP SETD8 SP1 SPIB TFDP1 TFDP2 YY1
Entrez ID		29028	1870
HPRD ID		10678	02692
Ensembl ID		ENSG00000156802	ENSG00000007968
Uniprot IDs		Q6PL18	Q14209
PDB IDs		3DAI	1N4M
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Lens Fiber Cell Apoptotic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Fibroblast Proliferation Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Cell Cycle RNA Biosynthetic Process Mitotic Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Fibroblast Proliferation Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Vagina Development Regulation Of RNA Metabolic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Notch Signaling Pathway RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Female Genitalia Development Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Chromatin Remodeling Chromatin Modification Branching Morphogenesis Of An Epithelial Tube Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Homeostatic Process Morphogenesis Of A Branching Epithelium Chromatin Organization Morphogenesis Of A Branching Structure Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Cell Proliferation Genitalia Development Mammary Gland Duct Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Enucleate Erythrocyte Differentiation Positive Regulation Of Cellular Biosynthetic Process Mitotic Cell Cycle Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Division Positive Regulation Of Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Androgen Receptor Signaling Pathway DNA-templated Transcription, Initiation Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Growth Factor Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Modification Response To Growth Factor Negative Regulation Of Transcription, DNA-templated Sequestering Of Nodal From Receptor Via Nodal Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process
Tagcloud ?		acted ancca budding bulk compaction deviations dosage driver entering facilitating hta1 internucleosomal locally metagene nucleosomal nucleosome nucleosomes ortholog profound progressively reflected rtt106 shifted shifts spacing transcriptionally ways yta7 yta7delta	accordingly acting collectively documented downregulates escc esophageal exerted harbor heterogeneity inactive microrna micrornas mir negatively oncogenes p21 personalized pleiotropically reversed speculate stk40 subgroup supporting suppressive te undetectable upstream virtually
Tagcloud (Difference) ?		acted ancca budding bulk compaction deviations dosage driver entering facilitating hta1 internucleosomal locally metagene nucleosomal nucleosome nucleosomes ortholog profound progressively reflected rtt106 shifted shifts spacing transcriptionally ways yta7 yta7delta	accordingly acting collectively documented downregulates escc esophageal exerted harbor heterogeneity inactive microrna micrornas mir negatively oncogenes p21 personalized pleiotropically reversed speculate stk40 subgroup supporting suppressive te undetectable upstream virtually
Tagcloud (Intersection) ?