BCAR3 and GLCE

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		BCAR3	GLCE
Description		BCAR3 adaptor protein, NSP family member	glucuronic acid epimerase
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GO Annotations	Cellular Component	Cytoplasm Focal Adhesion Membrane Anchoring Junction	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	Calcium Ion Binding Isomerase Activity Racemase And Epimerase Activity, Acting On Carbohydrates And Derivatives Protein Homodimerization Activity Metal Ion Binding Heparosan-N-sulfate-glucuronate 5-epimerase Activity
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Small GTPase-mediated Signal Transduction Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Endothelin Receptor Signaling Pathway	Positive Regulation Of Cell Population Proliferation Heparan Sulfate Proteoglycan Biosynthetic Process Heparin Proteoglycan Biosynthetic Process Negative Regulation Of Cell Projection Organization Positive Regulation Of SMAD Protein Signal Transduction
Pathways			HS-GAG biosynthesis
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)	Blood protein levels ( 30072576)
Interacting Genes		38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 DRC4 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45	11 interacting genes: BAG4 BCAR3 CASP8 ERBB2 ESR1 FBXO7 FGFR2 FGFR4 PAX2 PPM1D RB1CC1
Entrez ID		8412	26035
HPRD ID		05268	07020
Ensembl ID		ENSG00000137936	ENSG00000138604
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	O94923
PDB IDs		3T6A	6HZZ 6I01 6I02
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity ERBB2 Signaling Pathway Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Basal Plasma Membrane Protein Tyrosine Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Epithelial Cell Proliferation Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Epithelial Cell Proliferation ERBB3:ERBB2 Complex Response To Epidermal Growth Factor Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Regulation Of Cell Population Proliferation Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Epithelial Cell Proliferation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Molecular Function Inhibitor Activity Positive Regulation Of Phosphate Metabolic Process Response To Growth Factor Regulation Of Protein Modification Process Protein Kinase Activity Positive Regulation Of Lymphocyte Migration Positive Chemotaxis ERBB2-EGFR Signaling Pathway Growth Factor Binding Regulation Of Primary Metabolic Process Cell Population Proliferation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Basolateral Plasma Membrane Positive Regulation Of Cell Migration Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway	Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Population Proliferation Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Population Proliferation Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Prostate Epithelial Cord Elongation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Fibroblast Growth Factor Receptor Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAPK Cascade Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Negative Regulation Of Apoptotic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Prostate Gland Growth Regulation Of Catalytic Activity Branching Involved In Prostate Gland Morphogenesis Positive Regulation Of Signal Transduction Branch Elongation Of An Epithelium Regulation Of MAPK Cascade Stem Cell Differentiation Positive Regulation Of Metabolic Process Axis Elongation Regulation Of Metabolic Process Protein Tyrosine Kinase Activity Fibroblast Growth Factor Binding Prostate Gland Epithelium Morphogenesis Response To Lipid Morphogenesis Of A Branching Epithelium Morphogenesis Of Embryonic Epithelium Morphogenesis Of A Branching Structure Animal Organ Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Epithelial Tube Formation Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Signal Transduction Cellular Response To Epidermal Growth Factor Stimulus Organ Growth Positive Regulation Of Macromolecule Biosynthetic Process Response To Epidermal Growth Factor Regulation Of Morphogenesis Of A Branching Structure Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Cell Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow
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