ATAD2 and E2F3

Number of citations of the paper that reports this interaction (PMID 20855524)
12

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ATAD2	E2F3
Gene Name		ATPase family, AAA domain containing 2	E2F transcription factor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	ATP Binding ATPase Activity	Core Promoter Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription, DNA-templated
Pathways			Signaling by NOTCH DNA Replication Pre-Initiation G1 Phase Cellular Senescence M/G1 Transition Regulation of DNA replication CDC6 association with the ORC:origin complex Oncogene Induced Senescence Cell Cycle, Mitotic Assembly of the pre-replicative complex Cyclin D associated events in G1 Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence G2 Phase Pre-NOTCH Expression and Processing Association of licensing factors with the pre-replicative complex Mitotic G2-G2/M phases Mitotic G1-G1/S phases
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		9 interactors: E2F1 E2F2 E2F3 E2F4 ESR1 HIST2H4A HIST3H3 MYC NCOA3	23 interactors: ATAD2 CCNA2 CDK3 CREBBP FHL2 FZR1 HCFC1 HELLS MGA MYBL2 PKIB RB1 RNF144A RYBP SP1 SPIB SRA1 TEAD3 TFDP1 TFDP2 TFE3 WNK1 YY1
Entrez ID		29028	1871
HPRD ID		10678	02693
Ensembl ID		ENSG00000156802	ENSG00000112242
Uniprot IDs		Q6PL18	O00716 Q24JQ3
PDB IDs		3DAI
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Lens Fiber Cell Apoptotic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Fibroblast Proliferation Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Cell Cycle RNA Biosynthetic Process Mitotic Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Fibroblast Proliferation Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Vagina Development Regulation Of RNA Metabolic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Notch Signaling Pathway RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Female Genitalia Development Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Chromatin Remodeling Chromatin Modification Branching Morphogenesis Of An Epithelial Tube Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Homeostatic Process Morphogenesis Of A Branching Epithelium Chromatin Organization Morphogenesis Of A Branching Structure Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Cell Proliferation Genitalia Development Mammary Gland Duct Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Positive Regulation Of Metabolic Process Mitotic Nuclear Division Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Cell Cycle DNA-templated Transcription, Initiation Mitotic Cell Cycle Process Regulation Of Cellular Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cellular Metabolic Process Cell Cycle Process Cell Division Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Enucleate Erythrocyte Differentiation Negative Regulation Of Gene Expression Negative Regulation Of Transferase Activity Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle
Tagcloud ?		acted ancca budding bulk compaction deviations dosage driver entering facilitating hta1 internucleosomal locally metagene nucleosomal nucleosome nucleosomes ortholog profound progressively reflected rtt106 shifted shifts spacing transcriptionally ways yta7 yta7delta	34a arrest carcinogenic chemokine concern concerned creates ct cytotoxicity doses frequent greatly involves ionizing killer mammographies medical micro mir mirna overexposure pathways patterns presentation radiation ray scans successfully workers
Tagcloud (Difference) ?		acted ancca budding bulk compaction deviations dosage driver entering facilitating hta1 internucleosomal locally metagene nucleosomal nucleosome nucleosomes ortholog profound progressively reflected rtt106 shifted shifts spacing transcriptionally ways yta7 yta7delta	34a arrest carcinogenic chemokine concern concerned creates ct cytotoxicity doses frequent greatly involves ionizing killer mammographies medical micro mir mirna overexposure pathways patterns presentation radiation ray scans successfully workers
Tagcloud (Intersection) ?