CCDC22 and ACTG1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CCDC22	ACTG1
Gene Name		coiled-coil domain containing 22	actin gamma 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Extracellular Space Nucleus Cytosol Cytoskeleton Plasma Membrane Membrane Myofibril Filamentous Actin Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Molecular_function Protein Binding Cullin Family Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Cellular Copper Ion Homeostasis Golgi To Plasma Membrane Transport Cytoplasmic Sequestering Of NF-kappaB Biological_process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Retina Homeostasis Movement Of Cell Or Subcellular Component Axon Guidance Cell Junction Assembly Adherens Junction Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Sarcomere Organization Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Membrane Organization Platelet Aggregation
Pathways			Axon guidance Gap junction degradation Adherens junctions interactions Translocation of GLUT4 to the plasma membrane L1CAM interactions Recycling pathway of L1 VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Interaction between L1 and Ankyrins Cell-cell junction organization EPH-ephrin mediated repulsion of cells Gap junction trafficking and regulation EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System Cell junction organization Formation of annular gap junctions Gap junction trafficking Signaling by VEGF Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ACTG1 BLOC1S6 CPNE1 CPNE4 USHBP1	60 interactors: ABLIM1 ACTB ANXA5 APOE ATF7IP BCAP31 BRCA1 CAP1 CAP2 CAPZA3 CCDC22 CDKN2A CFL1 CFL2 COTL1 CTBP2 CTTN CYBB DISC1 DNASE1 DSTN DYNLL1 EHHADH EIF6 FHOD1 FPR1 GIT2 GSN GZMA GZMK LGALS13 LIG4 LSP1 MAP1A MAPK6 MYO1A MYOC NDRG1 NR3C2 PFN2 PLD1 PLEC PPP1R9A PRSS23 PSEN2 PTPRO RPS6KA5 SCIN SH3GL2 ST3GAL3 SUMO4 TMSB4X TMSB4Y TNIK VASP VIL1 WASF1 WASL WDYHV1 WIPF1
Entrez ID		28952	71
HPRD ID		06594	00017
Ensembl ID		ENSG00000101997	ENSG00000184009
Uniprot IDs		O60826	P63261
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Secretion Of Lysosomal Enzymes Blood Coagulation Hemostasis Endosome To Melanosome Transport Pigment Granule Maturation Synaptic Vesicle Docking Cellular Pigment Accumulation Positive Regulation Of Pigment Cell Differentiation Regulation Of Body Fluid Levels Positive Regulation Of Developmental Pigmentation Wound Healing Anterograde Synaptic Vesicle Transport Response To Wounding Melanosome Organization Pigment Granule Organization Regulation Of Developmental Pigmentation Positive Regulation Of Natural Killer Cell Activation Anterograde Axon Cargo Transport Neuron Projection Development Membrane Organization Positive Regulation Of Immune System Process Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanocyte Differentiation Neuron Development Platelet Aggregation Melanosome Localization Neuroepithelial Cell Differentiation Axon Cargo Transport Sarcomere Organization Neuron Differentiation Cell Projection Organization Synaptic Vesicle Exocytosis Cellular Pigmentation Retina Homeostasis Vesicle Docking Involved In Exocytosis Developmental Pigmentation Regulation Of Immune System Process Transport Myofibril Assembly Vesicle Docking Post-Golgi Vesicle-mediated Transport Adherens Junction Organization Movement Of Cell Or Subcellular Component Membrane Docking Ephrin Receptor Signaling Pathway Generation Of Neurons Vascular Endothelial Growth Factor Receptor Signaling Pathway	Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Organelle Organization Organelle Organization Regulation Of Cellular Component Size Chemotaxis Cell Projection Organization Neurogenesis Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Depolymerization Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Complex Assembly Neuron Projection Development Negative Regulation Of Protein Polymerization Movement Of Cell Or Subcellular Component Axon Guidance Generation Of Neurons Actin Filament Severing Positive Regulation Of Cellular Component Biogenesis Locomotion Regulation Of Protein Depolymerization Cell Development Response To External Stimulus Neuron Development Nervous System Development Axon Development Regulation Of Protein Complex Disassembly Regulation Of Cell Projection Organization Actin Filament Depolymerization Neuron Projection Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Actin Filament Polymerization Signal Transduction
Tagcloud ?			alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Difference) ?			alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Intersection) ?