GRB7 and INSR

  • Number of citations of the paper that reports this interaction (PMID 10803466)
  • 12
  • Data Source:
  • BioGRID (two hybrid, pull down)
  • HPRD (in vitro, in vivo, two hybrid)

GRB7

INSR

Gene Name growth factor receptor-bound protein 7 insulin receptor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 39 interactors: A1BG AGAP1 ATP5B CALM1 CAV1 CPNE6 DOCK7 DYNC1I1 EGFR ERBB2 ERBB3 FGB FLAD1 GNB2 GRB2 HADHB INSR KCTD6 KIT KMT2B LAX1 LY6G6F MAP3K14 MSH2 PDGFRB PDHB PHAX PKM PTK2 RET RND1 RPS2 SETDB1 SHC1 TEK TLE1 TMSB4X TRIM36 ZBTB16 77 interactors: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 ENPP1 FABP4 FRS2 GAB1 GNB2L1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B SYNCRIP TEAD1 VAV1 VAV3 YWHAB
Entrez ID 2886 3643
HPRD ID 03311 00975
Ensembl ID ENSG00000141738 ENSG00000171105
Uniprot IDs Q14451 P06213
PDB IDs 1MW4 1WGR 2L4K 2QMS 3PQZ 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3LOH 3W11 3W12 3W13 3W14 4IBM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adapter  appears  avidly  bear  bps  conversely  denote  domain  domains  dramatically  existence  grb10  grb14  homology  interact  interaction  interacts  ir  location  loop  obvious  paired  pleckstrin  resemblance  sh2  summary  unidentified  y1150f  y1151f 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Difference) ?
adapter  appears  avidly  bear  bps  conversely  denote  domain  domains  dramatically  existence  grb10  grb14  homology  interact  interaction  interacts  ir  location  loop  obvious  paired  pleckstrin  resemblance  sh2  summary  unidentified  y1150f  y1151f 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Intersection) ?