SCARA5 and WASHC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCARA5	WASHC3
Description		scavenger receptor class A member 5	WASH complex subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane	Endosome Early Endosome Early Endosome Membrane WASH Complex
	Molecular Function	Protein Binding Ferritin Receptor Activity	Protein Binding
	Biological Process	Monoatomic Ion Transport Iron Ion Transport Intracellular Iron Ion Homeostasis Endocytosis Cellular Response To Heat Iron Ion Transmembrane Transport Protein Homotrimerization	Exocytosis Protein Transport Endosomal Transport Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Age-related cognitive decline (executive function) (slope of z-scores) ( 30954325) Factor VIII levels ( 30586737) Lack of premeditation ( 30718321) Low vWF levels ( 26486471) Venous thromboembolism ( 31420334) vWF levels ( 30586737)	Appendicular lean mass ( 33097823)
Interacting Genes		16 interacting genes: C1QL4 CMTM5 EHHADH EXOC8 FBXO7 KANK2 NTAQ1 P4HA3 PSMB1 RNF151 SLC35B4 SMARCD1 SNCA TMEM208 TSG101 WASHC3	55 interacting genes: ABI2 BFSP2 BLOC1S2 BLOC1S6 C20orf202 CCDC197 CCHCR1 CENPK CEP55 CKAP4 COG6 DTNBP1 GDF9 GNG13 GOLGA2 HAUS1 HSBP1 HSPB1 IFT20 IKBIP KDM1A KNSTRN KRT27 KRT6A KRT71 KRT75 LAMC1 LHX4 LMNB2 LUC7L2 MCRS1 MOB1A MOB1B MYOZ1 NDC80 NUP62 OPTN PAX6 PBXIP1 PCM1 PHOSPHO2 PTN RABEP1 SCARA5 SDCBP SNAP25 SNAPIN SRGAP2B SYCE1 TEX35 TFIP11 TXLNA TXLNB VPS52 WASHC1
Entrez ID		286133	51019
HPRD ID		11356	13031
Ensembl ID		ENSG00000168079	ENSG00000120860
Uniprot IDs		Q6ZMJ2	F5GWI9 F5GZ97 Q9Y3C0
PDB IDs		7C00
Enriched GO Terms of Interacting Partners?		Exocytosis Regulation Of Cell Cycle G1/S Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Secretion By Cell Membrane Fission Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Protein-N-terminal Glutamine Amidohydrolase Activity UDP-xylose Transmembrane Transport UDP-xylose Transmembrane Transporter Activity Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Secretion Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Ubiquitin-dependent Endocytosis Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Vitamin D Receptor Signaling Pathway Vacuolar Protein Processing Protein-N-terminal Asparagine Amidohydrolase Activity	Organelle Organization BLOC-1 Complex Cytoskeleton Organization Establishment Of Organelle Localization Organelle Localization Axon Cytoplasm Cytoskeleton Axonal Transport Transport Along Microtubule Microtubule-based Process Axo-dendritic Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Anterograde Axonal Transport Microtubule-based Transport Syntaxin Binding Cellular Localization Supramolecular Fiber Organization Establishment Of Localization In Cell Intermediate Filament Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Establishment Of Protein Localization Organelle Transport Along Microtubule Intermediate Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Vesicle Transport Along Microtubule Intracellular Transport Centrosome Cycle Establishment Of Vesicle Localization Intracellular Protein Localization Protein Transport Vesicle Cytoskeletal Trafficking Microtubule-based Movement Structural Constituent Of Skin Epidermis Vesicle Localization Organelle Assembly Neuron Projection Development Spindle Pole Microtubule Organizing Center Organization Centriole Keratin Filament Mitotic Sister Chromatid Segregation Membraneless Organelle Assembly Localization Within Membrane Regulation Of Lysosome Size BORC Complex Sister Chromatid Segregation
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