SCARA5

Name	scavenger receptor class A member 5
Structure
Interactors	16 interactors: C1QL4 CMTM5 EHHADH EXOC8 FBXO7 KANK2 NTAQ1 P4HA3 PSMB1 RNF151 SLC35B4 SMARCD1 SNCA TMEM208 TSG101 WASHC3
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding Ferritin Receptor Activity
	Biological Process	Monoatomic Ion Transport Iron Ion Transport Intracellular Iron Ion Homeostasis Endocytosis Cellular Response To Heat Iron Ion Transmembrane Transport Protein Homotrimerization
Pathways	Scavenging by Class A Receptors
GWAS	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065 ) Age-related cognitive decline (executive function) (slope of z-scores) ( 30954325 ) Factor VIII levels ( 30586737 ) Lack of premeditation ( 30718321 ) Low vWF levels ( 26486471 ) Venous thromboembolism ( 31420334 ) vWF levels ( 30586737 )
Entrez ID	286133
HPRD ID	11356
Ensembl ID	ENSG00000168079
Uniprot IDs	Q6ZMJ2
PDB IDs	7C00
GO Terms Enriched among Interactors ?	Exocytosis Regulation Of Cell Cycle G1/S Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Secretion By Cell Membrane Fission Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Protein-N-terminal Glutamine Amidohydrolase Activity UDP-xylose Transmembrane Transport UDP-xylose Transmembrane Transporter Activity Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Secretion Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Ubiquitin-dependent Endocytosis Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Vitamin D Receptor Signaling Pathway Vacuolar Protein Processing Protein-N-terminal Asparagine Amidohydrolase Activity