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GPR25 and NAALADL2
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
GPR25
NAALADL2
Description
G protein-coupled receptor 25
N-acetylated alpha-linked acidic dipeptidase like 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Nucleoplasm
Membrane
Molecular Function
G Protein-coupled Receptor Activity
Protein Binding
Protein Binding
Biological Process
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Response To Bacterium
Pathways
G alpha (s) signalling events
Drugs
Diseases
GWAS
Ankylosing spondylitis (
23749187
)
Autoimmune thyroid disease (
32581359
)
Refractive error (
32231278
)
3-month functional outcome in ischaemic stroke (modified Rankin score) (
30796134
)
Autism spectrum disorder (
26398136
)
Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) (
33012170
)
Deep ovarian and/or rectovaginal disease with dense adhesions (
28333195
)
Familial lung adenocarcinoma (
29924316
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Height (
23456168
)
Idiopathic downbeat nystagmus (
32157568
)
Influenza A (H1N1) severity (
26379185
)
Kawasaki disease (
19132087
)
Loneliness (
27629369
)
Metabolite levels (MHPG) (
23319000
)
Mitochondrial DNA copy number (
30704525
)
Number of sexual partners (
30643258
)
Priapism in sickle cell disease (
31668730
)
Prostate cancer aggressiveness (
25939597
)
Rapid automised naming of pictures (
30741946
)
Response to alcohol consumption (flushing response) (
29460428
)
Sleep duration (
23728906
)
Systemic lupus erythematosus (
21408207
)
Triglyceride levels in HIV infection (
33109212
)
Interacting Genes
32 interacting genes:
AQP6
ATP6V0C
ATP6V0E1
BEST2
CNIH4
CREB3L1
CREB3L3
FATE1
GGT7
GJB1
IKBIP
KASH5
LDLRAD1
LMNA
MAP3K7
MMGT1
NAALADL2
PNMA1
RETN
RHCG
SHISAL1
SLC16A7
SLC35E3
SLC61A1
SLCO4A1
STOM
TMEM237
TMEM248
TMEM52B
TPRA1
TSPAN12
VAPB
6 interacting genes:
APP
GPR25
GRM2
ITM2B
LAPTM4B
SLC30A3
Entrez ID
2848
254827
HPRD ID
03707
16388
Ensembl ID
ENSG00000170128
ENSG00000177694
Uniprot IDs
O00155
Q58DX5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Membrane
Carbon Dioxide Transmembrane Transporter Activity
Transmembrane Transport
Carbon Dioxide Transmembrane Transport
Ammonium Transmembrane Transport
Ammonium Channel Activity
Proton-transporting V-type ATPase, V0 Domain
Host-mediated Activation Of Viral Genome Replication
Endoplasmic Reticulum Membrane
Host-mediated Perturbation Of Viral Genome Replication
Carbon Dioxide Transport
Protein Binding
Proton-transporting V-type ATPase Complex
Response To Unfolded Protein
Intracellular Monoatomic Ion Homeostasis
Proton-transporting ATPase Activity, Rotational Mechanism
Regulation Of PH
One-carbon Compound Transport
Basolateral Plasma Membrane
Monoatomic Ion Transport
Astrocyte Projection
Endosome
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Amyloid-beta Complex
Glutamate Receptor Signaling Pathway
Growth Cone Lamellipodium
Neuron Projection
Plasma Membrane
Regulation Of Response To Calcium Ion
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Zinc Ion Import Into Synaptic Vesicle
Lysosome
Acetylcholine Receptor Activator Activity
PTB Domain Binding
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Endosome To Plasma Membrane Transport Vesicle
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Lipoprotein Particle
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Import
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
Group II Metabotropic Glutamate Receptor Activity
Hippocampal Mossy Fiber
Regulation Of Lysosomal Membrane Permeability
Response To Norepinephrine
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Intermediate-density Lipoprotein Particle
Axon Midline Choice Point Recognition
Positive Regulation Of Amyloid Fibril Formation
Adult Behavior
Cellular Response To Norepinephrine Stimulus
G Protein-coupled Receptor Signaling Pathway
Growth Factor Receptor Binding
Main Axon
Astrocyte Activation Involved In Immune Response
Low-density Lipoprotein Particle Mediated Signaling
Late Endosome Membrane
Zinc Ion Import Into Lysosome
Negative Regulation Of Lysosomal Protein Catabolic Process
Multivesicular Body, Internal Vesicle
Regulation Of Spontaneous Synaptic Transmission
Regulation Of Synaptic Plasticity
NMDA Selective Glutamate Receptor Signaling Pathway
Regulation Of Synapse Structure Or Activity
Regulation Of Toll Signaling Pathway
Intracellular Glutamate Homeostasis
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Tagcloud (Intersection)
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