GPR25 and SLCO4A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR25	SLCO4A1
Description		G protein-coupled receptor 25	solute carrier organic anion transporter family member 4A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Protein Binding Organic Anion Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway	Monoatomic Ion Transport Organic Anion Transport Prostaglandin Transport Sodium-independent Organic Anion Transport Transmembrane Transport Thyroid Hormone Transport
Pathways		G alpha (s) signalling events	Organic anion transport by SLCO transporters
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)	Macular thickness ( 30535121) Menopause (age at onset) ( 26414677)
Interacting Genes		32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLC61A1 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB	2 interacting genes: CCR4 GPR25
Entrez ID		2848	28231
HPRD ID		03707	11582
Ensembl ID		ENSG00000170128	ENSG00000101187
Uniprot IDs		O00155	Q96BD0
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Carbon Dioxide Transmembrane Transporter Activity Transmembrane Transport Carbon Dioxide Transmembrane Transport Ammonium Transmembrane Transport Ammonium Channel Activity Proton-transporting V-type ATPase, V0 Domain Host-mediated Activation Of Viral Genome Replication Endoplasmic Reticulum Membrane Host-mediated Perturbation Of Viral Genome Replication Carbon Dioxide Transport Protein Binding Proton-transporting V-type ATPase Complex Response To Unfolded Protein Intracellular Monoatomic Ion Homeostasis Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of PH One-carbon Compound Transport Basolateral Plasma Membrane Monoatomic Ion Transport	Chemokine Receptor Activity Interneuron Migration G Protein-coupled Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Tolerance Induction G Protein-coupled Receptor Signaling Pathway
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