GPR25 and TMEM248

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR25	TMEM248
Description		G protein-coupled receptor 25	transmembrane protein 248
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		G alpha (s) signalling events
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLC61A1 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB	27 interacting genes: ANKRD46 ARL6IP1 ARLN BARD1 BRICD5 CLDN19 FAM3C GPR25 GPR37L1 GRM2 LEPROTL1 LHFPL5 MAL MALL RUSF1 RXFP3 SLC35B2 SLC41A1 SYNE4 SYS1 TMEM147 TMEM239 TMEM86B TRARG1 VSTM1 YIF1A YIPF1
Entrez ID		2848	55069
HPRD ID		03707	08541
Ensembl ID		ENSG00000170128	ENSG00000106609
Uniprot IDs		O00155	Q9NWD8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Carbon Dioxide Transmembrane Transporter Activity Transmembrane Transport Carbon Dioxide Transmembrane Transport Ammonium Transmembrane Transport Ammonium Channel Activity Proton-transporting V-type ATPase, V0 Domain Host-mediated Activation Of Viral Genome Replication Endoplasmic Reticulum Membrane Host-mediated Perturbation Of Viral Genome Replication Carbon Dioxide Transport Protein Binding Proton-transporting V-type ATPase Complex Response To Unfolded Protein Intracellular Monoatomic Ion Homeostasis Proton-transporting ATPase Activity, Rotational Mechanism Regulation Of PH One-carbon Compound Transport Basolateral Plasma Membrane Monoatomic Ion Transport	Membrane Establishment Of Protein Localization To Membrane Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath
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