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ZSCAN1 and POLR2B
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
ZSCAN1
POLR2B
Gene Name
zinc finger and SCAN domain containing 1
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase II, Core Complex
Membrane
Molecular Function
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
DNA Binding
Transcription Coactivator Activity
Metal Ion Binding
RNA Polymerase II Activity
DNA Binding
Chromatin Binding
Protein Binding
Ribonucleoside Binding
Poly(A) RNA Binding
Metal Ion Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
MRNA Splicing, Via Spliceosome
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
RNA Splicing
Gene Expression
Viral Process
PiRNA Metabolic Process
Somatic Stem Cell Maintenance
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
PIWI-interacting RNA (piRNA) biogenesis
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Regulatory RNA pathways
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
Influenza Life Cycle
HIV elongation arrest and recovery
HIV Life Cycle
HIV Transcription Initiation
Influenza Viral RNA Transcription and Replication
RNA Pol II CTD phosphorylation and interaction with CE
Transcriptional regulation of pluripotent stem cells
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Transcriptional regulation by small RNAs
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
MicroRNA (miRNA) biogenesis
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Transcription-coupled NER (TC-NER)
Viral Messenger RNA Synthesis
Formation of the HIV-1 Early Elongation Complex
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Age-related macular degeneration (
21909106
)
Height (
20881960
)
Protein-Protein Interactions
38 interactors:
ANKRD55
APP
ASH2L
ATXN1
CDC5L
CDK4
CDK6
CNOT6L
ERCC3
FXR2
GOPC
GTF2E1
GTF2H1
HOPX
INSM2
MED21
MED31
MED7
NPAS2
PLRG1
POLR2B
POLR2D
POLR2E
PPARG
PPL
RFC1
SNW1
SSX3
SSX5
TAF7
TBX20
TIMELESS
TRIM31
TTF2
ZKSCAN5
ZNF263
ZNF396
ZNF407
18 interactors:
BTF3
CALM1
CCNH
CDK7
CTDP1
IKBKG
ITCH
LZTR1
MEN1
NEDD4
POLR2A
POLR2C
POLR2D
POLR2H
POLR2K
POLR2L
SUB1
ZSCAN1
Entrez ID
284312
5431
HPRD ID
15897
15943
Ensembl ID
ENSG00000152467
ENSG00000047315
Uniprot IDs
Q8NBB4
C9J2Y9
C9J4M6
P30876
PDB IDs
Enriched GO Terms of Interacting Partners
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Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Regulation Of Gene Expression
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of Nucleic Acid-templated Transcription
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
DNA-templated Transcription, Initiation
Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Viral Transcription
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
MRNA Processing
Negative Regulation Of Gene Expression
RNA Processing
Positive Regulation Of Cellular Biosynthetic Process
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
MRNA Metabolic Process
Regulation Of Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Positive Regulation Of Viral Process
7-methylguanosine RNA Capping
DNA-templated Transcription, Elongation
Regulation Of Viral Process
Nucleotide-excision Repair
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Metabolic Process
Positive Regulation Of Viral Transcription
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
7-methylguanosine RNA Capping
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Transcription-coupled Nucleotide-excision Repair
DNA-templated Transcription, Elongation
Viral Process
Regulation Of Viral Process
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Nucleotide-excision Repair
DNA-templated Transcription, Initiation
PiRNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Termination Of RNA Polymerase I Transcription
Somatic Stem Cell Maintenance
Transcription Elongation From RNA Polymerase I Promoter
Transcription, DNA-templated
Transcription Initiation From RNA Polymerase I Promoter
RNA Biosynthetic Process
Transcription From RNA Polymerase I Promoter
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Metabolic Process
DNA Repair
MRNA Processing
Stem Cell Maintenance
Regulation Of Metabolic Process
RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Stress
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
MRNA Metabolic Process
Gene Expression
RNA Processing
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
MRNA Splicing, Via Spliceosome
Regulation Of Type I Interferon Production
RNA Splicing, Via Transesterification Reactions
Stem Cell Development
DNA Metabolic Process
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