POLR2B and BTF3

Number of citations of the paper that reports this interaction (PMID 2320128)
23

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		POLR2B	BTF3
Gene Name		polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	basic transcription factor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DNA-directed RNA Polymerase II, Core Complex Membrane	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Activity DNA Binding Chromatin Binding Protein Binding Ribonucleoside Binding Poly(A) RNA Binding Metal Ion Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping RNA Splicing Gene Expression Viral Process PiRNA Metabolic Process Somatic Stem Cell Maintenance Positive Regulation Of Viral Transcription	In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Protein Transport
Pathways		RNA Polymerase II Promoter Escape mRNA Splicing Formation of HIV-1 elongation complex containing HIV-1 Tat PIWI-interacting RNA (piRNA) biogenesis Nucleotide Excision Repair RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Regulatory RNA pathways Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Influenza Life Cycle HIV elongation arrest and recovery HIV Life Cycle HIV Transcription Initiation Influenza Viral RNA Transcription and Replication RNA Pol II CTD phosphorylation and interaction with CE Transcriptional regulation of pluripotent stem cells RNA Polymerase II HIV Promoter Escape HIV Transcription Elongation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation by small RNAs Processing of Capped Intron-Containing Pre-mRNA mRNA Capping mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway MicroRNA (miRNA) biogenesis Influenza Infection Pausing and recovery of Tat-mediated HIV elongation Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex RNA Polymerase II Transcription Initiation And Promoter Clearance Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) Viral Messenger RNA Synthesis Formation of the HIV-1 Early Elongation Complex RNA Polymerase II Transcription Initiation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Age-related macular degeneration ( 21909106) Height ( 20881960)
Protein-Protein Interactions		18 interactors: BTF3 CALM1 CCNH CDK7 CTDP1 IKBKG ITCH LZTR1 MEN1 NEDD4 POLR2A POLR2C POLR2D POLR2H POLR2K POLR2L SUB1 ZSCAN1	9 interactors: APP CSNK2B ESR1 MED21 NACA POLR2B TXLNA TXLNB ZDHHC17
Entrez ID		5431	689
HPRD ID		15943	03966
Ensembl ID		ENSG00000047315	ENSG00000145741
Uniprot IDs		C9J2Y9 C9J4M6 P30876	P20290
PDB IDs			3LKX 3MCB
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Transcription Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping 7-methylguanosine RNA Capping Regulation Of Viral Transcription Positive Regulation Of Viral Process Transcription-coupled Nucleotide-excision Repair DNA-templated Transcription, Elongation Viral Process Regulation Of Viral Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Nucleotide-excision Repair DNA-templated Transcription, Initiation PiRNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Termination Of RNA Polymerase I Transcription Somatic Stem Cell Maintenance Transcription Elongation From RNA Polymerase I Promoter Transcription, DNA-templated Transcription Initiation From RNA Polymerase I Promoter RNA Biosynthetic Process Transcription From RNA Polymerase I Promoter Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Positive Regulation Of Metabolic Process DNA Repair MRNA Processing Stem Cell Maintenance Regulation Of Metabolic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Stress DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic MRNA Metabolic Process Gene Expression RNA Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process MRNA Splicing, Via Spliceosome Regulation Of Type I Interferon Production RNA Splicing, Via Transesterification Reactions Stem Cell Development DNA Metabolic Process	Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Developmental Growth Cell Development Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Growth Positive Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Hormone-mediated Signaling Pathway Collateral Sprouting In Absence Of Injury Positive Regulation Of Skeletal Muscle Tissue Growth Prostate Epithelial Cord Elongation Developmental Growth Involved In Morphogenesis Regulation Of Cell Differentiation Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Cell Differentiation Anatomical Structure Development Regulation Of Organ Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway RNA Metabolic Process Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Regulation Of Transcription From RNA Polymerase II Promoter Axon Choice Point Recognition Cell Differentiation Gene Expression DNA-templated Transcription, Initiation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Developmental Process Adiponectin-activated Signaling Pathway Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Cellular Macromolecule Biosynthetic Process Steroid Metabolic Process Stem Cell Development Neuron Remodeling Regulation Of Binding Macromolecule Biosynthetic Process
Tagcloud ?			anxa2 astrocytic astrocytoma bayesian blanket cd99 cdk4 col4a1 dramatically engineering glioblastoma hubs influential joint lifetime machine markov movement mpp2 multiforme network nfkbeta options rab31 seemed serbp1 top top2a validate
Tagcloud (Difference) ?			anxa2 astrocytic astrocytoma bayesian blanket cd99 cdk4 col4a1 dramatically engineering glioblastoma hubs influential joint lifetime machine markov movement mpp2 multiforme network nfkbeta options rab31 seemed serbp1 top top2a validate
Tagcloud (Intersection) ?