ZSCAN1 and TAF7

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZSCAN1	TAF7
Description		zinc finger and SCAN domain containing 1	TATA-box binding protein associated factor 7
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Male Germ Cell Nucleus Nucleus Nucleoplasm Transcription Regulator Complex Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Transcription Cis-regulatory Region Binding TFIIH-class Transcription Factor Complex Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Nuclear Vitamin D Receptor Binding Nuclear Thyroid Hormone Receptor Binding Protein Heterodimerization Activity Histone H3K27me3 Reader Activity P-TEFb Complex Binding DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport Regulation Of DNA Repair Chromatin Organization DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Estrogen Receptor Signaling Pathway MRNA Transcription By RNA Polymerase II Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways			HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS			Mean platelet volume ( 27863252 32888494) Refractive error ( 32231278)
Interacting Genes		40 interacting genes: ANKRD55 APP ASH2L ATXN1 CDC5L CDK6 CNOT6L ERCC3 FXR2 GOPC GTF2E1 GTF2H1 HOPX INSM2 MED21 MED31 MED7 NFYC NPAS2 PLRG1 POLR2B POLR2D POLR2E PPARG PPL RFC1 SH2D2A SNW1 SSX3 SSX5 TAF7 TBX20 TIMELESS TRIM31 TTF2 ZKSCAN5 ZNF263 ZNF396 ZNF407 ZSCAN22	28 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B OGT RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1
Entrez ID		284312	6879
HPRD ID		15897	07196
Ensembl ID		ENSG00000152467	ENSG00000178913
Uniprot IDs		Q8NBB4	Q15545
PDB IDs			4RGW 5FUR 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus DNA Binding Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II DNA-templated Transcription Initiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process RNA Metabolic Process Positive Regulation Of Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process DNA-templated Transcription Nucleic Acid Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II Preinitiation Complex Assembly RNA Polymerase II, Core Complex Negative Regulation Of Transcription By RNA Polymerase II DNA Damage Response Negative Regulation Of RNA Metabolic Process Transcription Preinitiation Complex Assembly Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Initiation By RNA Polymerase II Core Mediator Complex Regulation Of DNA-templated Transcription Initiation U2-type Catalytic Step 2 Spliceosome DNA-directed RNA Polymerase Activity Nucleoplasm Transcription Factor TFIID Complex Macromolecule Biosynthetic Process	DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription Transcription Preinitiation Complex Assembly Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Factor TFTC Complex DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Protein-DNA Complex Assembly Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Heterodimerization Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Repair RNA Metabolic Process MRNA Metabolic Process Nucleoplasm Positive Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of RNA Metabolic Process Nucleus Protein-containing Complex Organization Positive Regulation Of Macromolecule Metabolic Process Protein-containing Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Positive Regulation Of Metabolic Process Nucleic Acid Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Metabolic Process Macromolecule Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process SAGA Complex Regulation Of Primary Metabolic Process TBP-class Protein Binding
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