ZSCAN1 and NPAS2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZSCAN1	NPAS2
Gene Name		zinc finger and SCAN domain containing 1	neuronal PAS domain protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Transcription Factor Complex Cytosol
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Transcription Coactivator Activity Metal Ion Binding	Core Promoter Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Protein Binding Metal Ion Binding Protein Dimerization Activity Hsp90 Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Signal Transduction Central Nervous System Development Circadian Rhythm Circadian Regulation Of Gene Expression Circadian Sleep/wake Cycle Cellular Lipid Metabolic Process Small Molecule Metabolic Process Locomotor Rhythm Positive Regulation Of DNA Repair Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Redox State Negative Regulation Of Cell Death Regulation Of Response To DNA Damage Stimulus
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) REV-ERBA represses gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression RORA activates circadian gene expression
Drugs
Diseases
GWAS			Creutzfeldt-Jakob disease (variant) ( 22137330)
Protein-Protein Interactions		38 interactors: ANKRD55 APP ASH2L ATXN1 CDC5L CDK4 CDK6 CNOT6L ERCC3 FXR2 GOPC GTF2E1 GTF2H1 HOPX INSM2 MED21 MED31 MED7 NPAS2 PLRG1 POLR2B POLR2D POLR2E PPARG PPL RFC1 SNW1 SSX3 SSX5 TAF7 TBX20 TIMELESS TRIM31 TTF2 ZKSCAN5 ZNF263 ZNF396 ZNF407	19 interactors: ARNT2 ARNTL ARNTL2 CREBBP CRX EFS EP300 HESX1 HGS HSP90AA1 KAT2B NCOA3 RARA RASSF7 RHOXF1 RPL6 RXRA TRAF4 ZSCAN1
Entrez ID		284312	4862
HPRD ID		15897	09137
Ensembl ID		ENSG00000152467	ENSG00000170485
Uniprot IDs		Q8NBB4	A2I2P5 F5H027 Q99743
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated DNA-templated Transcription, Initiation Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Viral Transcription Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter MRNA Processing Negative Regulation Of Gene Expression RNA Processing Positive Regulation Of Cellular Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription MRNA Metabolic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Positive Regulation Of Viral Process 7-methylguanosine RNA Capping DNA-templated Transcription, Elongation Regulation Of Viral Process Nucleotide-excision Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process	RNA Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression N-terminal Protein Amino Acid Acetylation Rhythmic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Signal Transduction Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Communication Biosynthetic Process Cellular Nitrogen Compound Metabolic Process N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Histone Acetylation Regulation Of Cellular Process Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Cellular Response To Stimulus Transcription Initiation From RNA Polymerase II Promoter Circadian Rhythm Response To Stimulus Intracellular Receptor Signaling Pathway Embryo Development Cellular Response To Heat Intracellular Steroid Hormone Receptor Signaling Pathway
Tagcloud ?			additively bmal1 box circadian clock electrophoretic ems fold heme heterodimer homodimer kd kinetics luciferase maximal metabolite mixture mobility monoxide nad nadph nih3t3 ph rhythms sense sensor shift truncated
Tagcloud (Difference) ?			additively bmal1 box circadian clock electrophoretic ems fold heme heterodimer homodimer kd kinetics luciferase maximal metabolite mixture mobility monoxide nad nadph nih3t3 ph rhythms sense sensor shift truncated
Tagcloud (Intersection) ?