NAPRT and RBPMS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NAPRT	RBPMS
Gene Name		nicotinate phosphoribosyltransferase	RNA binding protein with multiple splicing
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm
	Molecular Function	Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity Nicotinate Phosphoribosyltransferase Activity Ligase Activity	Nucleotide Binding Transcription Coactivator Activity Protein Binding Poly(A) Binding Poly(A) RNA Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Nicotinamide Metabolic Process Response To Oxidative Stress NAD Biosynthetic Process Nicotinate Nucleotide Salvage NAD Metabolic Process Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Nicotinamide salvaging Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Nicotinate metabolism Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS			Heart rate variability traits ( 22174390)
Protein-Protein Interactions		5 interactors: CCDC57 EHMT2 GRAMD3 KRT40 RBPMS	174 interactors: ADAM15 AES AMMECR1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0E2 ATXN1 BANP BBS2 BCL6B BHLHE40 BOLL C11orf87 C1orf111 C1orf94 C20orf195 C22orf39 C9orf24 CAMK2B CCER1 CCNG1 CCNK CDC23 CDC42EP1 CNNM3 CRBN CREB5 CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DMRT3 DOK3 DOK6 DPYSL4 DTX2 DVL2 EFEMP2 ENKD1 EWSR1 EYA2 FAM103A1 FAM124B FAM168A FASTK FBF1 FBXL18 FOXC2 FOXP3 FOXS1 FXR2 GCM2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 HEY2 HEYL HNRNPLL HOXA1 HOXA9 HOXB9 IGF2 ILF3 INCA1 INIP IP6K2 KCTD9 KIF1A KIR2DL4 KPNA2 KRAS KRTAP12-2 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP8-1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LMO4 LOC142937 LOC148413 LONRF1 LRRC41 LRRC75A-AS1 LZTS2 MAGED1 MCM5 MGAT5B MVP MYOZ2 NAB2 NAPRT NEDD9 NEU4 NR1D2 NYNRIN OTX1 PAPD4 PDLIM4 PER1 PGLS PHF1 PIH1D1 PIN1 PITX1 PLAC8 POGZ POM121 PRKAA1 PRKAA2 PRKAB2 PRR20A QKI R3HDM2 RABL6 RBFOX1 RBFOX2 RDH12 RHOBTB3 RHOXF2 RIPPLY1 ROR2 RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SH3RF2 SIRPB1 SMUG1 SNRPB SNRPC SPATA8 SPG7 STRBP TBX6 TEX37 TFG TIE1 TINAGL1 TMSB4X TOLLIP TOR1AIP2 TRIP13 TTLL10 TUSC2 VENTX VHL VHLL VPS37C WDR54 WDR90 WDYHV1 YPEL3 ZBTB32 ZC3H10 ZNF385C ZNF488 ZNF581
Entrez ID		93100	11030
HPRD ID		15161	11870
Ensembl ID		ENSG00000147813	ENSG00000157110
Uniprot IDs		Q6XQN6	B4E3T4 D3DSV0 Q93062
PDB IDs			1BNY
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Within A CG Sequence Histone H3-K27 Methylation Peptidyl-lysine Dimethylation DNA Methylation On Cytosine Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of SMAD Protein Import Into Nucleus Histone H3-K9 Methylation Synaptonemal Complex Assembly Synaptonemal Complex Organization Histone H3-K9 Modification	RNA Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Developmental Process Regulation Of Cellular Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Response To Stimulus Cellular Response To Stimulus Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Signaling Signal Transduction Cellular Metabolic Process Cell Communication Positive Regulation Of Macromolecule Biosynthetic Process System Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Anterior/posterior Pattern Specification Biosynthetic Process Regulation Of Circadian Rhythm Organ Development Insulin Receptor Signaling Pathway Cellular Process Response To Radiation
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