GLP1R and MYL6

Number of citations of the paper that reports this interaction (PMID 23864651)
0

Data Source:
BioGRID (protein complementation assay, affinity chromatography technology)

		GLP1R	MYL6
Gene Name		glucagon-like peptide 1 receptor	myosin, light chain 6, alkali, smooth muscle and non-muscle
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Cytosol Membrane Myosin Complex Unconventional Myosin Complex Vesicle Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Glucagon Receptor Activity	Motor Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Actin-dependent ATPase Activity
	Biological Process	Energy Reserve Metabolic Process Response To Stress G-protein Coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Learning Or Memory Regulation Of Heart Contraction CAMP-mediated Signaling Small Molecule Metabolic Process Regulation Of Insulin Secretion Cellular Response To Glucagon Stimulus	Muscle Contraction Axon Guidance Skeletal Muscle Tissue Development Metabolic Process Muscle Filament Sliding Ephrin Receptor Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Integration of energy metabolism G alpha (s) signalling events Regulation of insulin secretion Glucagon-type ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)	EPHA-mediated growth cone collapse Axon guidance Semaphorin interactions Smooth Muscle Contraction EPH-Ephrin signaling Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs		Glucagon recombinant Exenatide Liraglutide
Diseases
GWAS
Protein-Protein Interactions		41 interactors: ACSF3 APH1A ARFRP1 ATP13A1 C14orf166 C18orf32 CALM1 CAND2 CEND1 CFI CYSTM1 ELOVL1 ERP29 GABBR2 GCG GPR37 GPRASP1 HPN IFITM3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MFSD5 MRPL22 MYL6 NOTCH2NL NRGN NUCKS1 P4HTM PAQR6 PIGG SLC15A4 STMN1 STMN3 STOML2 SUMO1 SVOP SYNGR3 TMEM147 TSPAN13	7 interactors: ADAMTS12 DNAJB9 EWSR1 GLP1R MLH1 MOB4 NUDT21
Entrez ID		2740	4637
HPRD ID		00677	17618
Ensembl ID		ENSG00000112164	ENSG00000092841
Uniprot IDs		P43220	B7Z6Z4 F8VZU9 G3V1Y7 P60660 Q6IBG5
PDB IDs		3C59 3C5T 3IOL
Enriched GO Terms of Interacting Partners?		Microtubule Depolymerization Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Substantia Nigra Development Microtubule Polymerization Or Depolymerization Cerebellar Granular Layer Maturation Positive Regulation Of Cardiolipin Metabolic Process Protein Unfolding Positive Regulation Of Mitochondrial DNA Replication Stress-induced Mitochondrial Fusion Malonate Catabolic Process Molybdate Ion Transport	MRNA 3'-end Processing Negative Regulation Of Cellular Response To Hepatocyte Growth Factor Stimulus Meiotic Spindle Midzone Assembly Negative Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Meiotic Metaphase I Plate Congression RNA 3'-end Processing Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Mitotic Recombination Proteoglycan Catabolic Process Regulation Of Mitotic Recombination Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Male Meiosis Chromosome Segregation Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus Spindle Midzone Assembly
Tagcloud ?		2a cardiac cardiomyopathies cardioprotective ccaat chaperone chemoattractant chop endoplasmic ex4 exendin fibrosis glucagon gluco grp78 homologous incretin infarction infiltration lipotoxicity mcp1 mhc monocyte reperfusion reticulum sarco serca2a viable
Tagcloud (Difference) ?		2a cardiac cardiomyopathies cardioprotective ccaat chaperone chemoattractant chop endoplasmic ex4 exendin fibrosis glucagon gluco grp78 homologous incretin infarction infiltration lipotoxicity mcp1 mhc monocyte reperfusion reticulum sarco serca2a viable
Tagcloud (Intersection) ?