MYL6 and MOB4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYL6	MOB4
Gene Name		myosin, light chain 6, alkali, smooth muscle and non-muscle	MOB family member 4, phocein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Myosin Complex Unconventional Myosin Complex Vesicle Extracellular Vesicular Exosome	Cytoplasm Golgi Apparatus Cytosol Golgi Cisterna Membrane Neuronal Cell Body Dendritic Spine Perinuclear Region Of Cytoplasm
	Molecular Function	Motor Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Actin-dependent ATPase Activity	Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Muscle Contraction Axon Guidance Skeletal Muscle Tissue Development Metabolic Process Muscle Filament Sliding Ephrin Receptor Signaling Pathway	Transport
Pathways		EPHA-mediated growth cone collapse Axon guidance Semaphorin interactions Smooth Muscle Contraction EPH-Ephrin signaling Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ADAMTS12 DNAJB9 EWSR1 GLP1R MLH1 MOB4 NUDT21	31 interactors: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2
Entrez ID		4637	25843
HPRD ID		17618	10165
Ensembl ID		ENSG00000092841	ENSG00000115540
Uniprot IDs		B7Z6Z4 F8VZU9 G3V1Y7 P60660 Q6IBG5	B4DM50 Q9Y3A3
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA 3'-end Processing Negative Regulation Of Cellular Response To Hepatocyte Growth Factor Stimulus Meiotic Spindle Midzone Assembly Negative Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Meiotic Metaphase I Plate Congression RNA 3'-end Processing Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Mitotic Recombination Proteoglycan Catabolic Process Regulation Of Mitotic Recombination Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Male Meiosis Chromosome Segregation Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus Spindle Midzone Assembly	Developmental Process Anatomical Structure Development Cell Differentiation Positive Regulation Of Protein Metabolic Process Multicellular Organismal Development Regulation Of Metabolic Process Regulation Of Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cellular Metabolic Process Hippo Signaling Regulation Of Protein Metabolic Process Regulation Of Neuron Projection Development Signal Transduction Positive Regulation Of Neuron Projection Development System Development Cellular Response To Stimulus Regulation Of Cellular Component Organization Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Signaling Neurogenesis Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cell Projection Organization Regulation Of Cell Projection Organization Cell Communication Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Neuron Projection Development Regulation Of Phosphorus Metabolic Process Cellular Response To Organic Substance Nervous System Development Cell Projection Organization Regulation Of Signal Transduction Cell Projection Morphogenesis Response To Stimulus Positive Regulation Of Catalytic Activity Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Cell Part Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Death
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