MYL6

Description		myosin light chain 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Brush Border Membrane Myosin Complex Myosin II Complex Unconventional Myosin Complex Vesicle Extracellular Exosome
	Molecular Function	Microfilament Motor Activity Cytoskeletal Motor Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle
	Biological Process	Muscle Contraction Skeletal Muscle Tissue Development Muscle Filament Sliding
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Asthma ( 31619474)
Novel Interacting Genes		1 novel interacting genes: CYP27B1
Interacting Genes		11 interacting genes: ADAMTS12 CEBPA DNAJB9 EWSR1 FNDC3B GLP1R GSK3B HMGB2 MLH1 MOB4 NUDT21
Entrez ID		4637
HPRD ID		17618
Ensembl ID		ENSG00000092841
Uniprot IDs		P60660
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Peptide Response To Cytokine Positive Regulation Of Developmental Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Cell Differentiation Response To Hormone Regulation Of Cell Differentiation Regulation Of Developmental Process Calcidiol 1-monooxygenase Activity Secalciferol 1-monooxygenase Activity Glucagon-like Peptide 1 Receptor Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Microtubule Anchoring At Centrosome Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Condensed Chromosome Somatic Cell DNA Recombination Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Positive Regulation Of Pro-B Cell Differentiation Negative Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Response To Hepatocyte Growth Factor Stimulus Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Immunoglobulin Production Positive Regulation Of Gene Expression Response To Vitamin Response To Vitamin B2 C/EBP Complex Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Apoptotic Signaling Pathway Non-sequence-specific DNA Binding, Bending Regulation Of Immunoglobulin Production Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Stem Cell Differentiation Regulation Of Multicellular Organismal Process Regulation Of Stem Cell Proliferation Response To Lipid CHOP-C/EBP Complex Cellular Response To Tumor Necrosis Factor Vitamin D Biosynthetic Process Calcitriol Biosynthetic Process From Calciol Vitamin D Catabolic Process Glucagon Receptor Activity Negative Regulation Of Signal Transduction Male Meiosis Chromosome Segregation
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