GLP1R and ERP29

Number of citations of the paper that reports this interaction (PMID 23864651)
0

Data Source:
BioGRID (protein complementation assay, affinity chromatography technology)

		GLP1R	ERP29
Gene Name		glucagon-like peptide 1 receptor	endoplasmic reticulum protein 29
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cell Surface Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Glucagon Receptor Activity	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Energy Reserve Metabolic Process Response To Stress G-protein Coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Learning Or Memory Regulation Of Heart Contraction CAMP-mediated Signaling Small Molecule Metabolic Process Regulation Of Insulin Secretion Cellular Response To Glucagon Stimulus	Activation Of MAPK Activity Positive Regulation Of Protein Phosphorylation Protein Folding Intracellular Protein Transport Protein Secretion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Protein Unfolding Negative Regulation Of Protein Secretion
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Integration of energy metabolism G alpha (s) signalling events Regulation of insulin secretion Glucagon-type ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs		Glucagon recombinant Exenatide Liraglutide
Diseases
GWAS
Protein-Protein Interactions		41 interactors: ACSF3 APH1A ARFRP1 ATP13A1 C14orf166 C18orf32 CALM1 CAND2 CEND1 CFI CYSTM1 ELOVL1 ERP29 GABBR2 GCG GPR37 GPRASP1 HPN IFITM3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MFSD5 MRPL22 MYL6 NOTCH2NL NRGN NUCKS1 P4HTM PAQR6 PIGG SLC15A4 STMN1 STMN3 STOML2 SUMO1 SVOP SYNGR3 TMEM147 TSPAN13	3 interactors: GLP1R HSPA5 UBQLN4
Entrez ID		2740	10961
HPRD ID		00677	03794
Ensembl ID		ENSG00000112164	ENSG00000089248
Uniprot IDs		P43220	P30040
PDB IDs		3C59 3C5T 3IOL	2QC7
Enriched GO Terms of Interacting Partners?		Microtubule Depolymerization Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Substantia Nigra Development Microtubule Polymerization Or Depolymerization Cerebellar Granular Layer Maturation Positive Regulation Of Cardiolipin Metabolic Process Protein Unfolding Positive Regulation Of Mitochondrial DNA Replication Stress-induced Mitochondrial Fusion Malonate Catabolic Process Molybdate Ion Transport	Regulation Of Protein Folding In Endoplasmic Reticulum Cerebellum Structural Organization
Tagcloud ?		2a cardiac cardiomyopathies cardioprotective ccaat chaperone chemoattractant chop endoplasmic ex4 exendin fibrosis glucagon gluco grp78 homologous incretin infarction infiltration lipotoxicity mcp1 mhc monocyte reperfusion reticulum sarco serca2a viable	1s alga augments box brown calmodulin camkii cascade cascades ccaat chop eif2alpha exerts fucoidan fucose grp78 hct116 inositol ire killing marine mb mda metastatic modulating polysaccharide requiring splicing xbp
Tagcloud (Difference) ?		2a cardiac cardiomyopathies cardioprotective chaperone chemoattractant endoplasmic ex4 exendin fibrosis glucagon gluco homologous incretin infarction infiltration lipotoxicity mcp1 mhc monocyte reperfusion reticulum sarco serca2a viable	1s alga augments box brown calmodulin camkii cascade cascades eif2alpha exerts fucoidan fucose hct116 inositol ire killing marine mb mda metastatic modulating polysaccharide requiring splicing xbp
Tagcloud (Intersection) ?		ccaat chop grp78