ERP29 and C3orf52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERP29	C3orf52
Description		endoplasmic reticulum protein 29	chromosome 3 open reading frame 52
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Cell Surface Membrane Melanosome	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Homodimerization Activity Protein-folding Chaperone Binding	Protein Binding
	Biological Process	Protein Folding Intracellular Protein Transport Protein Secretion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Protein Unfolding Positive Regulation Of MAPK Cascade Negative Regulation Of Protein Secretion Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)	Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494)
Interacting Genes		21 interacting genes: ADIPOQ BMP10 C3orf52 CEBPA CTNNBL1 DESI1 GLP1R HMG20B HSPA5 NRM PUF60 SGTA SGTB SLC35B4 SLC38A7 TMBIM6 TMEM86B TSPO2 UBQLN1 UBQLN2 UBQLN4	74 interacting genes: ADGRG3 AGER AHNAK2 AMIGO1 AQP6 ATP1B4 BIK CCL21 CCL26 CD33 CHST13 CLDN7 CLEC10A CNMD CPLX4 CREB3 DEXI ERGIC3 ERP29 ESAM FAM209A FFAR2 FKBP7 FNDC9 FOLH1 FUT3 GJA8 GJB1 GOLM2 GORAB GPX8 HHLA2 HSD17B13 KEL KIR2DL3 KLRC1 LEUTX LHFPL5 LMNA LRRC25 MFF MGST2 MGST3 MRGPRX3 MUC1 NCR3LG1 NEMP1 NPDC1 NSG2 PVR QPCTL REEP3 RNF150 SAR1A SGTA SLC10A1 SLC10A2 SLC10A6 SLC16A2 SLC23A2 SLC39A2 SPRING1 ST6GALNAC3 STOM SYNE4 TIMMDC1 TMEM179B TMEM237 TMEM45B TMEM52B TMEM80 TMPRSS2 UPK2 ZNRF3
Entrez ID		10961	79669
HPRD ID		03794	08018
Ensembl ID		ENSG00000089248	ENSG00000114529
Uniprot IDs		P30040 V9HW71	Q5BVD1
PDB IDs		2QC7 5V8Z 5V90
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress TRC Complex Positive Regulation Of ERAD Pathway Regulation Of Protein Catabolic Process Regulation Of Proteolysis ERAD Pathway Regulation Of ERAD Pathway Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteasomal Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Identical Protein Binding Negative Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Membrane, Translocation Regulation Of Cellular Response To Stress Regulation Of Protein Metabolic Process Endoplasmic Reticulum Regulation Of Ubiquitin-dependent Protein Catabolic Process IRE1-mediated Unfolded Protein Response Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Autophagosome Regulation Of IRE1-mediated Unfolded Protein Response Protein-containing Complex Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Cellular Localization Positive Regulation Of Protein Metabolic Process Autophagy Brown Fat Cell Differentiation Protein Targeting To ER Intracellular Protein Transmembrane Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Receptor-mediated Endocytosis Establishment Of Protein Localization To Endoplasmic Reticulum RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Integrated Stress Response Signaling Glucagon-like Peptide 1 Receptor Activity Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Protein Folding In Endoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Store-operated Calcium Channel Activity	Membrane Protein Binding Bile Acid:sodium Symporter Activity Plasma Membrane Glutathione Peroxidase Activity Bile Acid And Bile Salt Transport Leukotriene-C4 Synthase Activity
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