ERP29 and GLP1R

Number of citations of the paper that reports this interaction (PMID 23864651)
0

Data Source:
BioGRID (protein complementation assay, affinity chromatography technology)

		ERP29	GLP1R
Gene Name		endoplasmic reticulum protein 29	glucagon-like peptide 1 receptor
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cell Surface Membrane Melanosome Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	Transmembrane Signaling Receptor Activity Glucagon Receptor Activity
	Biological Process	Activation Of MAPK Activity Positive Regulation Of Protein Phosphorylation Protein Folding Intracellular Protein Transport Protein Secretion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Protein Unfolding Negative Regulation Of Protein Secretion	Energy Reserve Metabolic Process Response To Stress G-protein Coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Learning Or Memory Regulation Of Heart Contraction CAMP-mediated Signaling Small Molecule Metabolic Process Regulation Of Insulin Secretion Cellular Response To Glucagon Stimulus
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Integration of energy metabolism G alpha (s) signalling events Regulation of insulin secretion Glucagon-type ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs			Glucagon recombinant Exenatide Liraglutide
Diseases
GWAS
Protein-Protein Interactions		3 interactors: GLP1R HSPA5 UBQLN4	41 interactors: ACSF3 APH1A ARFRP1 ATP13A1 C14orf166 C18orf32 CALM1 CAND2 CEND1 CFI CYSTM1 ELOVL1 ERP29 GABBR2 GCG GPR37 GPRASP1 HPN IFITM3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MFSD5 MRPL22 MYL6 NOTCH2NL NRGN NUCKS1 P4HTM PAQR6 PIGG SLC15A4 STMN1 STMN3 STOML2 SUMO1 SVOP SYNGR3 TMEM147 TSPAN13
Entrez ID		10961	2740
HPRD ID		03794	00677
Ensembl ID		ENSG00000089248	ENSG00000112164
Uniprot IDs		P30040	P43220
PDB IDs		2QC7	3C59 3C5T 3IOL
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Folding In Endoplasmic Reticulum Cerebellum Structural Organization	Microtubule Depolymerization Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Substantia Nigra Development Microtubule Polymerization Or Depolymerization Cerebellar Granular Layer Maturation Positive Regulation Of Cardiolipin Metabolic Process Protein Unfolding Positive Regulation Of Mitochondrial DNA Replication Stress-induced Mitochondrial Fusion Malonate Catabolic Process Molybdate Ion Transport
Tagcloud ?		1s alga augments box brown calmodulin camkii cascade cascades ccaat chop eif2alpha exerts fucoidan fucose grp78 hct116 inositol ire killing marine mb mda metastatic modulating polysaccharide requiring splicing xbp	2a cardiac cardiomyopathies cardioprotective ccaat chaperone chemoattractant chop endoplasmic ex4 exendin fibrosis glucagon gluco grp78 homologous incretin infarction infiltration lipotoxicity mcp1 mhc monocyte reperfusion reticulum sarco serca2a viable
Tagcloud (Difference) ?		1s alga augments box brown calmodulin camkii cascade cascades eif2alpha exerts fucoidan fucose hct116 inositol ire killing marine mb mda metastatic modulating polysaccharide requiring splicing xbp	2a cardiac cardiomyopathies cardioprotective chaperone chemoattractant endoplasmic ex4 exendin fibrosis glucagon gluco homologous incretin infarction infiltration lipotoxicity mcp1 mhc monocyte reperfusion reticulum sarco serca2a viable
Tagcloud (Intersection) ?		ccaat chop grp78