CHMP3

Gene Name		charged multivesicular body protein 3
Image
Gene Ontology Annotations	Cellular Component	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding
	Biological Process	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Regulation Of Viral Process Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-protein Interactions		12 interactors: APP CHMP2A CHMP2B CHMP4A CHMP4B IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2
Entrez ID		51652
HPRD ID		15650
Ensembl ID		ENSG00000115561
Uniprot IDs		Q9Y3E7
PDB IDs		2GD5 2XZE 3FRT 3FRV
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Mitotic Metaphase Plate Congression Metaphase Plate Congression Viral Budding Establishment Of Chromosome Localization Cell Separation After Cytokinesis Mitotic Sister Chromatid Segregation Virion Assembly Sister Chromatid Segregation Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cell Division Regulation Of Mitotic Spindle Organization Endosomal Transport Vacuolar Transport Membrane Budding Chromosome Segregation Mitotic Nuclear Division Nucleus Organization Establishment Of Organelle Localization Mitotic Cell Cycle Process Negative Regulation Of Autophagic Vacuole Assembly Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Centrosome Duplication Organelle Localization Regulation Of Centrosome Cycle Vesicle-mediated Transport Viral Life Cycle Osteoblast Fate Commitment Regulation Of Cell Cycle Process Intracellular Transport Vesicle Organization Cell Cycle Process Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Regulation Of Cellular Component Organization Establishment Of Localization In Cell Negative Regulation Of Macroautophagy Establishment Of Protein Localization To Organelle Cell Cycle Regulation Of Autophagic Vacuole Assembly Protein Transport Regulation Of Mitotic Nuclear Division Establishment Of Protein Localization Regulation Of Vacuole Organization Membrane Organization Cellular Response To BMP Stimulus Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death
Tagcloud ?		degradative depletion dramatic eap30 egfrs endocytic endocytosed endosomal endosomes equally escrt golgi internalization intraluminal lysosomes m6prs machinery multivesicular mves recycling redistribution reflecting sorting stam tgn trafficking tsg101 vps22 vps24