CHMP3 and CHMP2B

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP3	CHMP2B
Gene Name		charged multivesicular body protein 3	charged multivesicular body protein 2B
Image
Gene Ontology Annotations	Cellular Component	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome	Intracellular Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Regulation Of Viral Process Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Membrane Organization Regulation Of Mitotic Spindle Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP CHMP2A CHMP2B CHMP4A CHMP4B IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2	11 interactors: ATP5C1 CENPF CHMP3 DPY30 MALSU1 PHGDH PNMA1 TERF2IP TRAF2 USP54 USP8
Entrez ID		51652	25978
HPRD ID		15650	13174
Ensembl ID		ENSG00000115561	ENSG00000083937
Uniprot IDs		Q9Y3E7	B2RE76 Q9UQN3
PDB IDs		2GD5 2XZE 3FRT 3FRV	2JQK
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Mitotic Metaphase Plate Congression Metaphase Plate Congression Viral Budding Establishment Of Chromosome Localization Cell Separation After Cytokinesis Mitotic Sister Chromatid Segregation Virion Assembly Sister Chromatid Segregation Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cell Division Regulation Of Mitotic Spindle Organization Endosomal Transport Vacuolar Transport Membrane Budding Chromosome Segregation Mitotic Nuclear Division Nucleus Organization Establishment Of Organelle Localization Mitotic Cell Cycle Process Negative Regulation Of Autophagic Vacuole Assembly Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Centrosome Duplication Organelle Localization Regulation Of Centrosome Cycle Vesicle-mediated Transport Viral Life Cycle Osteoblast Fate Commitment Regulation Of Cell Cycle Process Intracellular Transport Vesicle Organization Cell Cycle Process Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Regulation Of Cellular Component Organization Establishment Of Localization In Cell Negative Regulation Of Macroautophagy Establishment Of Protein Localization To Organelle Cell Cycle Regulation Of Autophagic Vacuole Assembly Protein Transport Regulation Of Mitotic Nuclear Division Establishment Of Protein Localization Regulation Of Vacuole Organization Membrane Organization Cellular Response To BMP Stimulus Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death See more	Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of Mitochondrial Translation Regulation Of Organelle Organization Negative Regulation Of Chromosome Organization Cell Division
Tagcloud ?		degradative depletion dramatic eap30 egfrs endocytic endocytosed endosomal endosomes equally escrt golgi internalization intraluminal lysosomes m6prs machinery multivesicular mves recycling redistribution reflecting sorting stam tgn trafficking tsg101 vps22 vps24	c9orf72 complexities counseling ethical fad familial frame frontotemporal ftd fus genetics grn gwas helping hexanucleotide mapt modifying multifactorial navigate pathogenetic presenilin progranulin psen1 psen2 reading tarbdp tardna valosin vcp
Tagcloud (Difference) ?		degradative depletion dramatic eap30 egfrs endocytic endocytosed endosomal endosomes equally escrt golgi internalization intraluminal lysosomes m6prs machinery multivesicular mves recycling redistribution reflecting sorting stam tgn trafficking tsg101 vps22 vps24	c9orf72 complexities counseling ethical fad familial frame frontotemporal ftd fus genetics grn gwas helping hexanucleotide mapt modifying multifactorial navigate pathogenetic presenilin progranulin psen1 psen2 reading tarbdp tardna valosin vcp
Tagcloud (Intersection) ?