USP54 and CHMP1B

Number of citations of the paper that reports this interaction (PubMedID 19302785)
0

Data Source:
BioGRID (pull down)

		USP54	CHMP1B
Description		ubiquitin specific peptidase 54	charged multivesicular body protein 1B
Image
GO Annotations	Cellular Component		Autophagosome Membrane Kinetochore ESCRT III Complex Nuclear Pore Nucleoplasm Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Membrane Coat Midbody Late Endosome Membrane Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity K63-linked Deubiquitinase Activity	Protein Binding Protein Domain Specific Binding Identical Protein Binding MIT Domain Binding
	Biological Process	Proteolysis Protein Deubiquitination	Plasma Membrane Repair Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Regulation Of Centrosome Duplication Protein Transport Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Cell Division Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly
Pathways
Drugs
Diseases
GWAS		Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Metabolite levels ( 23823483)
Interacting Genes		89 interacting genes: ANKRD11 ANKS1A ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C CSTF2 CYSRT1 DMRT3 DOK6 DTX2 DYRK1A EIF4E2 EPM2AIP1 EXOC8 FAM124B FBXO17 FNDC3B FOXI1 GCM2 HGS HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76	19 interacting genes: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN MITD1 PICK1 RAB11A RASSF7 SNCA SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B
Entrez ID		159195	57132
HPRD ID		15641	12106
Ensembl ID		ENSG00000166348	ENSG00000255112
Uniprot IDs		A0A7P0T9K1 B7Z7X1 Q70EL1	Q7LBR1
PDB IDs		8C61	3EAB 3JC1 4TXQ 4TXR 6E8G 6TZ4 6TZ5 6TZ9 8V2Q 8V2R 8V2S
Enriched GO Terms of Interacting Partners?		Membrane Fission ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Multivesicular Body Membrane Multivesicular Body-lysosome Fusion Viral Budding From Plasma Membrane Multivesicular Body Assembly Lysosomal Membrane Organization Multivesicular Body Organization Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Lysosome Transport Kinetochore Microtubule Mitotic Metaphase Chromosome Alignment Endosome Organization Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Viral Budding Nuclear Membrane Reassembly Mitotic Cytokinetic Process Protein Binding Metaphase Chromosome Alignment Plasma Membrane Repair ESCRT III Complex Disassembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Release From Host Cell ESCRT Complex Disassembly Regulation Of Spindle Assembly Regulation Of Transcription By RNA Polymerase II Cytokinetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Regulation Of Mitotic Spindle Organization Chromosome Localization Regulation Of Macromolecule Biosynthetic Process Multivesicular Body Regulation Of RNA Metabolic Process POZ Domain Binding Regulation Of Centrosome Duplication Nuclear Membrane Organization Regulation Of Primary Metabolic Process Autophagosome Maturation Autophagosome Membrane Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process	Cytokinetic Process Viral Budding Via Host ESCRT Complex Midbody Abscission Viral Budding Nuclear Membrane Reassembly Mitotic Cytokinetic Process Multivesicular Body Assembly Multivesicular Body Organization Viral Budding From Plasma Membrane Endosome Organization Cytoskeleton-dependent Cytokinesis Membrane Fission Mitotic Metaphase Chromosome Alignment Late Endosome To Lysosome Transport Midbody Nuclear Membrane Organization Multivesicular Body Sorting Pathway Metaphase Chromosome Alignment Membrane Assembly Mitotic Cytokinesis Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromosome Localization ESCRT III Complex Disassembly ESCRT Complex Disassembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Endosome Autophagosome Maturation Kinetochore Microtubule Protein-containing Complex Disassembly Viral Process Membrane Organization Regulation Of Mitotic Spindle Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Vesicle Organization Nuclear Pore Nucleus Organization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Multivesicular Body ESCRT III Complex Plasma Membrane Organization Amphisome Membrane Vesicle Fusion With Vacuole Lysosomal Transport Regulation Of Centrosome Duplication
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