INPP5J and TRIM54

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		INPP5J	TRIM54
Gene Name		inositol polyphosphate-5-phosphatase J	tripartite motif containing 54
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Plasma Membrane Growth Cone Dendritic Shaft	Microtubule Microtubule Associated Complex Z Disc
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity SH3 Domain Binding Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity	Signal Transducer Activity Microtubule Binding Zinc Ion Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Negative Regulation Of Peptidyl-serine Phosphorylation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation	Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organismal Development Cell Differentiation
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of IP3 and IP4 in the cytosol Synthesis of IP2, IP, and Ins in the cytosol Metabolism of lipids and lipoproteins Phospholipid metabolism Inositol phosphate metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CDC23 DNAJA3 EPS8 GOLGA2 TRIM27 TRIM54	127 interactors: ADCY4 ALS2CR11 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC67 CCDC87 CDK18 CDKN1A CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM STRA13 TBC1D22B TCEA2 TCEB3 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D3 UBE2I UBE2U UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 WDYHV1 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587
Entrez ID		27124	57159
HPRD ID		07573	05928
Ensembl ID		ENSG00000185133	ENSG00000138100
Uniprot IDs		Q15735	Q9BYV2
PDB IDs			3Q1D
Enriched GO Terms of Interacting Partners?		Regulation Of Organelle Organization Negative Regulation Of Transferase Activity Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Immune Response Positive Regulation Of Protein Ubiquitination Negative Regulation Of Interleukin-2 Secretion Mitotic Cell Cycle Regulation Of Cellular Component Organization Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Catalytic Activity Actin Polymerization-dependent Cell Motility Negative Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Metabolic Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Protein Ubiquitination Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Calcium Ion Import Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Exit From Mitosis Activation-induced Cell Death Of T Cells Interferon-gamma Secretion Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Proteolysis Behavioral Response To Ethanol Actin Filament Organization Mitotic Nuclear Division Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Protein Phosphorylation Regulation Of Cellular Component Size Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Complex Assembly Regulation Of Exit From Mitosis Mitochondrial DNA Replication Negative Regulation Of Proteolysis Cell Cycle Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Processing Negative Regulation Of Immune System Process Organelle Organization Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Phosphorylation Regulation Of Actin Filament-based Process Regulation Of Protein Processing	Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Organelle Organization Regulation Of Protein Catabolic Process Protein Metabolic Process Histone Deubiquitination RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Process Monoubiquitinated Protein Deubiquitination Histone Modification Gene Expression RNA Biosynthetic Process Chromatin Modification Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromatin Organization Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Chromosome Organization Cellular Response To Heat Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?