INPP5J

Gene Name		inositol polyphosphate-5-phosphatase J
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Plasma Membrane Growth Cone Dendritic Shaft
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity SH3 Domain Binding Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Negative Regulation Of Peptidyl-serine Phosphorylation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of IP3 and IP4 in the cytosol Synthesis of IP2, IP, and Ins in the cytosol Metabolism of lipids and lipoproteins Phospholipid metabolism Inositol phosphate metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: CDC23 DNAJA3 EPS8 GOLGA2 TRIM27 TRIM54
Entrez ID		27124
HPRD ID		07573
Ensembl ID		ENSG00000185133
Uniprot IDs		Q15735
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Organelle Organization Negative Regulation Of Transferase Activity Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Immune Response Positive Regulation Of Protein Ubiquitination Negative Regulation Of Interleukin-2 Secretion Mitotic Cell Cycle Regulation Of Cellular Component Organization Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Catalytic Activity Actin Polymerization-dependent Cell Motility Negative Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Metabolic Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Protein Ubiquitination Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Calcium Ion Import Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Exit From Mitosis Activation-induced Cell Death Of T Cells Interferon-gamma Secretion Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Proteolysis Behavioral Response To Ethanol Actin Filament Organization Mitotic Nuclear Division Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Protein Phosphorylation Regulation Of Cellular Component Size Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Complex Assembly Regulation Of Exit From Mitosis Mitochondrial DNA Replication Negative Regulation Of Proteolysis Cell Cycle Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Processing Negative Regulation Of Immune System Process Organelle Organization Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Phosphorylation Regulation Of Actin Filament-based Process Regulation Of Protein Processing
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