AKAP8L and RASAL3

		AKAP8L	RASAL3
Description		A-kinase anchoring protein 8 like	RAS protein activator like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	Cytoplasm Cytosol Cell Cortex Membrane Extracellular Exosome Cytoplasmic Side Of Membrane
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Identical Protein Binding
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	Negative Regulation Of Ras Protein Signal Transduction Positive Regulation Of NK T Cell Proliferation Regulation Of Intracellular Signal Transduction
Pathways		Formation of WDR5-containing histone-modifying complexes	Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)	Lymphocyte count ( 32888494)
Interacting Genes		60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	25 interacting genes: AMOTL2 BEGAIN CCDC102B CCDC136 CDR2L DEF6 HNRNPK HOMER1 KHDRBS3 KRT27 MAP1LC3A MAP1LC3B MTUS2 NTAQ1 PICK1 PPP1R13B PRKAA2 RABGEF1 RASD1 SNRPA TP53BP2 WASF3 YWHAE YWHAZ ZRANB1
Entrez ID		26993	64926
HPRD ID		10641	10977
Ensembl ID		ENSG00000011243	ENSG00000105122
Uniprot IDs		Q9ULX6	Q86YV0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum	Cytoplasm Cellular Response To Starvation Protein Domain Specific Binding Response To Starvation Cellular Response To Nutrient Levels Phosphoserine Residue Binding Cellular Response To Glucose Starvation Cellular Response To Nitrogen Starvation Vacuole Organization Arp2/3 Complex Binding Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Response To Nutrient Levels Hippo Signaling Protein Kinase A Regulatory Subunit Binding Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phospholipid Binding Intracellular Signal Transduction Ubiquitin Protein Ligase Binding Cytoskeleton Transmembrane Transporter Binding
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