RASAL3 and CDR2L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RASAL3	CDR2L
Description		RAS protein activator like 3	cerebellar degeneration related protein 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cell Cortex Membrane Extracellular Exosome Cytoplasmic Side Of Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Ras Protein Signal Transduction Positive Regulation Of NK T Cell Proliferation Regulation Of Intracellular Signal Transduction	Vesicle Transport Along Microtubule Golgi To Secretory Granule Transport
Pathways		Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494)	Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756)
Interacting Genes		25 interacting genes: AMOTL2 BEGAIN CCDC102B CCDC136 CDR2L DEF6 HNRNPK HOMER1 KHDRBS3 KRT27 MAP1LC3A MAP1LC3B MTUS2 NTAQ1 PICK1 PPP1R13B PRKAA2 RABGEF1 RASD1 SNRPA TP53BP2 WASF3 YWHAE YWHAZ ZRANB1	61 interacting genes: ANKRD11 BFSP2 C1orf216 C4orf46 CCDC146 CCDC185 CCDC187 CCHCR1 COX5B DRC12 EHHADH ELOA FAIM FAM161A FAM161B FAM86C1P HDAC4 HSF2BP INO80B KRT31 KRTAP13-4 LENG1 MESD OIP5 PPP1R18 PRPF31 RASAL3 RASD1 REL RINT1 SCNM1 SH2D4A SPMIP6 SPRY1 STX11 SVIP TBRG4 TCEANC TCHP TCP10L TFIP11 TSGA10IP UBE2I USP7 WASHC1 ZBTB42 ZNF19 ZNF250 ZNF35 ZNF417 ZNF572 ZNF629 ZNF648 ZNF655 ZNF669 ZNF688 ZNF80 ZNF835 ZSCAN22 ZSCAN23 ZSCAN26
Entrez ID		64926	30850
HPRD ID		10977	11041
Ensembl ID		ENSG00000105122	ENSG00000109089
Uniprot IDs		Q86YV0	Q86X02
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Cellular Response To Starvation Protein Domain Specific Binding Response To Starvation Cellular Response To Nutrient Levels Phosphoserine Residue Binding Cellular Response To Glucose Starvation Cellular Response To Nitrogen Starvation Vacuole Organization Arp2/3 Complex Binding Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Response To Nutrient Levels Hippo Signaling Protein Kinase A Regulatory Subunit Binding Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phospholipid Binding Intracellular Signal Transduction Ubiquitin Protein Ligase Binding Cytoskeleton Transmembrane Transporter Binding	Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
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