RASAL3 and KRT27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RASAL3	KRT27
Description		RAS protein activator like 3	keratin 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cell Cortex Membrane Extracellular Exosome Cytoplasmic Side Of Membrane	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Identical Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Negative Regulation Of Ras Protein Signal Transduction Positive Regulation Of NK T Cell Proliferation Regulation Of Intracellular Signal Transduction	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization
Pathways		Regulation of RAS by GAPs	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494)	Asthma ( 31959851)
Interacting Genes		25 interacting genes: AMOTL2 BEGAIN CCDC102B CCDC136 CDR2L DEF6 HNRNPK HOMER1 KHDRBS3 KRT27 MAP1LC3A MAP1LC3B MTUS2 NTAQ1 PICK1 PPP1R13B PRKAA2 RABGEF1 RASD1 SNRPA TP53BP2 WASF3 YWHAE YWHAZ ZRANB1	139 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80
Entrez ID		64926	342574
HPRD ID		10977	17244
Ensembl ID		ENSG00000105122	ENSG00000171446
Uniprot IDs		Q86YV0	Q7Z3Y8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Cellular Response To Starvation Protein Domain Specific Binding Response To Starvation Cellular Response To Nutrient Levels Phosphoserine Residue Binding Cellular Response To Glucose Starvation Cellular Response To Nitrogen Starvation Vacuole Organization Arp2/3 Complex Binding Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Response To Nutrient Levels Hippo Signaling Protein Kinase A Regulatory Subunit Binding Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phospholipid Binding Intracellular Signal Transduction Ubiquitin Protein Ligase Binding Cytoskeleton Transmembrane Transporter Binding	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Keratinization Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Organelle Organization Insulin Receptor Activity Structural Constituent Of Cytoskeleton Insulin Receptor Complex Intermediate Filament Cytoskeleton Structural Molecule Activity Insulin Receptor Substrate Binding Epidermis Development Brahma Complex NpBAF Complex RSC-type Complex NBAF Complex Phosphatidylinositol 3-kinase Binding Nucleosome Disassembly Insulin Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?