RASAL3 and BEGAIN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RASAL3	BEGAIN
Description		RAS protein activator like 3	brain enriched guanylate kinase associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cell Cortex Membrane Extracellular Exosome Cytoplasmic Side Of Membrane	Cytoplasm Membrane Synapse Postsynapse
	Molecular Function	GTPase Activator Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Ras Protein Signal Transduction Positive Regulation Of NK T Cell Proliferation Regulation Of Intracellular Signal Transduction	Evoked Excitatory Postsynaptic Potential
Pathways		Regulation of RAS by GAPs	Neurexins and neuroligins
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494)	Chronotype ( 30696823) Menarche (age at onset) ( 21102462) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		25 interacting genes: AMOTL2 BEGAIN CCDC102B CCDC136 CDR2L DEF6 HNRNPK HOMER1 KHDRBS3 KRT27 MAP1LC3A MAP1LC3B MTUS2 NTAQ1 PICK1 PPP1R13B PRKAA2 RABGEF1 RASD1 SNRPA TP53BP2 WASF3 YWHAE YWHAZ ZRANB1	47 interacting genes: ABLIM1 APP AQP1 ATPAF2 BAHD1 BMP7 CATSPER1 CDC23 DDX6 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A FAM161A FAM90A1 GEM GFI1B GMCL1 GUCD1 HDAC4 HGS HID1 KIAA0408 KIFC3 LENG1 MAB21L3 PRPF18 PRR35 QSOX1 RASAL3 RBL1 RIBC2 SAXO1 TRAF4 TRIM27 USP2 ZFP64 ZNF250 ZNF319 ZNF417 ZNF572 ZNF587 ZNF648 ZNF774 ZNF835
Entrez ID		64926	57596
HPRD ID		10977	06459
Ensembl ID		ENSG00000105122	ENSG00000183092
Uniprot IDs		Q86YV0	A0A1B0GTT1 G3V3A2 G3V3R5 Q9BUH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Cellular Response To Starvation Protein Domain Specific Binding Response To Starvation Cellular Response To Nutrient Levels Phosphoserine Residue Binding Cellular Response To Glucose Starvation Cellular Response To Nitrogen Starvation Vacuole Organization Arp2/3 Complex Binding Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Response To Nutrient Levels Hippo Signaling Protein Kinase A Regulatory Subunit Binding Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phospholipid Binding Intracellular Signal Transduction Ubiquitin Protein Ligase Binding Cytoskeleton Transmembrane Transporter Binding	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Zinc Ion Binding NMDA Selective Glutamate Receptor Signaling Pathway Protein Binding Regulation Of Mitotic Cell Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
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