GGT7 and GPR25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GGT7	GPR25
Gene Name		gamma-glutamyltransferase 7	G protein-coupled receptor 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Anchored Component Of External Side Of Plasma Membrane	Integral Component Of Plasma Membrane
	Molecular Function	Gamma-glutamyltransferase Activity Glutathione Hydrolase Activity	G-protein Coupled Receptor Activity
	Biological Process	Proteolysis Glutathione Metabolic Process Glutathione Biosynthetic Process Leukotriene Biosynthetic Process	G-protein Coupled Receptor Signaling Pathway
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Aflatoxin activation and detoxification Glutathione synthesis and recycling Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Glutathione conjugation Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: FAM57A GPR25 LHFPL5 MALL TMEM242	8 interactors: CCDC155 CREB3L1 FATE1 GGT7 MAP3K7 NAALADL2 PNMA1 VAPB
Entrez ID		2686	2848
HPRD ID		07488	03707
Ensembl ID		ENSG00000131067	ENSG00000170128
Uniprot IDs		A0PJJ9 Q9UJ14	O00155
PDB IDs
Enriched GO Terms of Interacting Partners?		Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Auditory Receptor Cell Development Inner Ear Receptor Stereocilium Organization Auditory Receptor Cell Differentiation Detection Of Mechanical Stimulus Involved In Sensory Perception Hair Cell Differentiation Inner Ear Receptor Cell Development Detection Of Mechanical Stimulus Inner Ear Receptor Cell Differentiation	Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Stress Cellular Response To Unfolded Protein Chromosome Localization To Nuclear Envelope Involved In Synapsis Negative Regulation By Host Of Viral Release From Host Cell ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Stress Response To Unfolded Protein Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Release From Host Cell Response To Endoplasmic Reticulum Stress Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Positive Regulation Of Viral Release From Host Cell Nitrogen Compound Metabolic Process I-kappaB Phosphorylation Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Necroptotic Process
Tagcloud ?			3p atherogenesis causality cdkn1b csf3 dedifferentiation experimentation genemania gpcr gpr1 gpr124 gpr171 gpr176 gpr32 gpr64 gprc5a hbp1 id2 il12 ingenuity intima moxldl nexus quiescent smc smcs themes transcriptomic zeb1
Tagcloud (Difference) ?			3p atherogenesis causality cdkn1b csf3 dedifferentiation experimentation genemania gpcr gpr1 gpr124 gpr171 gpr176 gpr32 gpr64 gprc5a hbp1 id2 il12 ingenuity intima moxldl nexus quiescent smc smcs themes transcriptomic zeb1
Tagcloud (Intersection) ?