GGT7

Gene Name		gamma-glutamyltransferase 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Anchored Component Of External Side Of Plasma Membrane
	Molecular Function	Gamma-glutamyltransferase Activity Glutathione Hydrolase Activity
	Biological Process	Proteolysis Glutathione Metabolic Process Glutathione Biosynthetic Process Leukotriene Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Aflatoxin activation and detoxification Glutathione synthesis and recycling Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Glutathione conjugation Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: FAM57A GPR25 LHFPL5 MALL TMEM242
Entrez ID		2686
HPRD ID		07488
Ensembl ID		ENSG00000131067
Uniprot IDs		A0PJJ9 Q9UJ14
PDB IDs
Enriched GO Terms of Interacting Partners?		Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Auditory Receptor Cell Development Inner Ear Receptor Stereocilium Organization Auditory Receptor Cell Differentiation Detection Of Mechanical Stimulus Involved In Sensory Perception Hair Cell Differentiation Inner Ear Receptor Cell Development Detection Of Mechanical Stimulus Inner Ear Receptor Cell Differentiation
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