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GCDH and RNF32
Number of citations of the paper that reports this interaction (PMID
21163940
)
13
Data Source:
BioGRID
(two hybrid)
GCDH
RNF32
Gene Name
glutaryl-CoA dehydrogenase
ring finger protein 32
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Endosome
Aggresome
Molecular Function
Fatty-acyl-CoA Binding
Glutaryl-CoA Dehydrogenase Activity
Flavin Adenine Dinucleotide Binding
Protein Binding
Zinc Ion Binding
Biological Process
Lysine Catabolic Process
Tryptophan Metabolic Process
Fatty Acid Oxidation
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Fatty-acyl-CoA Biosynthetic Process
Pathways
Lysine catabolism
Metabolism of amino acids and derivatives
Drugs
Flavin-Adenine Dinucleotide
S-4-Nitrobutyryl-Coa
Diseases
GWAS
Mean corpuscular hemoglobin (
19862010
)
Protein-Protein Interactions
10 interactors:
A2M
APOE
CDC37
ECSIT
EXOC6
MAST1
NOS3
PSEN1
PSEN2
RNF32
42 interactors:
A2M
APOE
APP
BLMH
CDC37
CDK5
CEP55
CYP2C8
CYP2C9
ECSIT
ELAVL3
EXOC6
EXOSC1
FARSA
FBXL12
FBXW4
FIBP
GCDH
HOXC4
IFIT3
IFIT5
LONP1
LOXL4
LZTS2
MAST1
MGEA5
MKRN3
MNAT1
NOS3
PAXIP1
PRAM1
PRDX2
PSEN1
PSEN2
RAB3A
RAB3D
RAD23A
RPP30
STAMBPL1
TRIM23
TRIM74
UBE2K
Entrez ID
2639
140545
HPRD ID
01977
11517
Ensembl ID
ENSG00000105607
ENSG00000105982
Uniprot IDs
Q92947
Q9H0A6
PDB IDs
1SIQ
1SIR
2R0M
2R0N
Enriched GO Terms of Interacting Partners
?
Regulation Of Oxidoreductase Activity
Regulation Of Catalytic Activity
Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Beta-amyloid Metabolic Process
Amyloid Precursor Protein Metabolic Process
Intracellular Signal Transduction
Nitric Oxide Mediated Signal Transduction
Negative Regulation Of Platelet Activation
Positive Regulation Of CGMP Biosynthetic Process
Protein Localization
Regulation Of Cellular Protein Metabolic Process
Membrane Protein Ectodomain Proteolysis
Notch Receptor Processing
Positive Regulation Of CGMP Metabolic Process
Establishment Of Localization In Cell
Regulation Of Synaptic Plasticity
Regulation Of CGMP Biosynthetic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Cell Differentiation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Protein Metabolic Process
Endoplasmic Reticulum Calcium Ion Homeostasis
Dorsal/ventral Neural Tube Patterning
Regulation Of Platelet Activation
Developmental Process
Regulation Of CGMP Metabolic Process
Cellular Localization
Positive Regulation Of Coagulation
Anatomical Structure Morphogenesis
Protein Transport
Membrane Protein Proteolysis
Myeloid Cell Differentiation
Brain Morphogenesis
Negative Regulation Of Apoptotic Signaling Pathway
Establishment Of Protein Localization
Regulation Of Nitric-oxide Synthase Activity
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Kinase Activity
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Cellular Calcium Ion Homeostasis
Regulation Of Signal Transduction
Calcium Ion Homeostasis
Regulation Of Synaptic Transmission
Blood Circulation
Thymus Development
Negative Regulation Of Protein Phosphorylation
Catabolic Process
Exocytosis
Synaptic Vesicle Exocytosis
Protein Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Cellular Protein Metabolic Process
Regulation Of Synaptic Plasticity
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Proteolysis
Response To Stress
Response To Stimulus
Endoplasmic Reticulum Calcium Ion Homeostasis
Secretion By Cell
Neurotransmitter Secretion
Synaptic Vesicle Transport
Regulation Of Protein Metabolic Process
Regulation Of Receptor Activity
Negative Regulation Of Cellular Protein Metabolic Process
Protein Catabolic Process
Cellular Response To Stimulus
Establishment Of Localization In Cell
Cellular Macromolecule Catabolic Process
Secretion
Regulation Of Neurotransmitter Levels
Negative Regulation Of Protein Metabolic Process
Amyloid Precursor Protein Catabolic Process
Omega-hydroxylase P450 Pathway
Regulation Of Protein Binding
Establishment Of Protein Localization
Cellular Metabolic Process
Neuron Apoptotic Process
Regulation Of Protein Tyrosine Kinase Activity
Vesicle Docking Involved In Exocytosis
Regulation Of Synaptic Transmission
Intracellular Signal Transduction
Positive Regulation Of Exocytosis
Neurotransmitter Transport
Negative Regulation Of Cell Death
Neuron Death
Regulation Of Protein Kinase Activity
Establishment Of Organelle Localization
Synapse Organization
Protein Localization
Metabolic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Oxidative Demethylation
Regulation Of Kinase Activity
Negative Regulation Of Neuron Differentiation
Regulation Of ERBB Signaling Pathway
Tagcloud
?
1031c
1109t
148t
628a
700c
731g
963g
aciduria
acidurias
athetosis
checked
cranial
drowsiness
dystonia
fissure
ganglia
glutaric
got
infant
intelligence
leukoencephalopathy
pediatrics
peking
psychomotor
retardation
sylvian
vomiting
w50r
widening
Tagcloud (Difference)
?
1031c
1109t
148t
628a
700c
731g
963g
aciduria
acidurias
athetosis
checked
cranial
drowsiness
dystonia
fissure
ganglia
glutaric
got
infant
intelligence
leukoencephalopathy
pediatrics
peking
psychomotor
retardation
sylvian
vomiting
w50r
widening
Tagcloud (Intersection)
?