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TIPRL and PPP4C
Number of citations of the paper that reports this interaction (PMID
16085932
)
43
Data Source:
BioGRID
(pull down)
TIPRL
PPP4C
Gene Name
TOR signaling pathway regulator
protein phosphatase 4, catalytic subunit
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Intracellular Membrane-bounded Organelle
Nucleus
Nucleoplasm
Cytoplasm
Microtubule Organizing Center
Plasma Membrane
Protein Phosphatase 4 Complex
Molecular Function
Protein Binding
NF-kappaB-inducing Kinase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Metal Ion Binding
Biological Process
DNA Damage Checkpoint
Negative Regulation Of Protein Phosphatase Type 2A Activity
Regulation Of Double-strand Break Repair Via Homologous Recombination
Dephosphorylation
NIK/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
APP
PPP2CB
PPP4C
PPP6C
20 interactors:
CCDC6
DHX38
HDAC3
IGBP1
JUN
NFKB1
PPP2R1A
PPP2R5D
PPP4R1
PPP4R2
PPP4R4
REL
RELA
SMEK2
TIPRL
TK1
TMSB4X
TP53
TRAF6
TRIM28
Entrez ID
261726
5531
HPRD ID
14608
03615
Ensembl ID
ENSG00000143155
ENSG00000149923
Uniprot IDs
O75663
P60510
PDB IDs
Enriched GO Terms of Interacting Partners
?
Dephosphorylation
Phosphate-containing Compound Metabolic Process
Synaptic Growth At Neuromuscular Junction
Cellular Protein Modification Process
Collateral Sprouting In Absence Of Injury
Protein Dephosphorylation
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Cellular Protein Metabolic Process
Neuron Remodeling
Response To Oxidative Stress
Regulation Of Double-strand Break Repair Via Homologous Recombination
Protein Metabolic Process
Cellular Copper Ion Homeostasis
Regulation Of Interleukin-12 Biosynthetic Process
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Toll-like Receptor 4 Signaling Pathway
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cellular Metabolic Process
Response To Growth Factor
Toll-like Receptor Signaling Pathway
Positive Regulation Of Interleukin-12 Biosynthetic Process
NIK/NF-kappaB Signaling
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Activation Of Innate Immune Response
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Interleukin-12 Production
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Innate Immune Response
Membrane Protein Intracellular Domain Proteolysis
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cell Death
Regulation Of Catalytic Activity
Response To Interleukin-1
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neurotrophin Signaling Pathway
Response To Organic Substance
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Innate Immune Response
Positive Regulation Of Gene Expression
Regulation Of Cell Death
Regulation Of Cytokine Biosynthetic Process
Innate Immune Response
Immune System Process
Membrane Protein Proteolysis
Transcription From RNA Polymerase II Promoter
Immune Response
Tagcloud
?
6j
acpp
canonical
carcinogenic
cdk5
delineate
e2f6
elf1
glands
gprc5a
hindered
ingenuity
ionizing
ipa
map2
mapk12
mapped
microarray
nab2
persistently
perturbed
plcg1
radiation
runx1
scarcity
sema4d
stathmin1
surgically
undertook
Tagcloud (Difference)
?
6j
acpp
canonical
carcinogenic
cdk5
delineate
e2f6
elf1
glands
gprc5a
hindered
ingenuity
ionizing
ipa
map2
mapk12
mapped
microarray
nab2
persistently
perturbed
plcg1
radiation
runx1
scarcity
sema4d
stathmin1
surgically
undertook
Tagcloud (Intersection)
?