PPP4C and IGBP1

Number of citations of the paper that reports this interaction (PMID 9647778)
44

Data Source:
HPRD (two hybrid)

		PPP4C	IGBP1
Gene Name		protein phosphatase 4, catalytic subunit	immunoglobulin (CD79A) binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Plasma Membrane Protein Phosphatase 4 Complex	Cytoplasm Microtubule
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding	Protein Binding Protein Phosphatase Type 2A Regulator Activity Protein Domain Specific Binding Mitogen-activated Protein Kinase Kinase Binding
	Biological Process	Regulation Of Double-strand Break Repair Via Homologous Recombination Dephosphorylation NIK/NF-kappaB Signaling	Negative Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Positive Regulation Of Dephosphorylation Negative Regulation Of Protein Dephosphorylation B Cell Activation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Microtubule-based Movement Response To Interleukin-1 Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: CCDC6 DHX38 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R4 REL RELA SMEK2 TIPRL TK1 TMSB4X TP53 TRAF6 TRIM28	9 interactors: APP LINC01257 LOC81691 MID1 MID2 PPP2CA PPP4C PPP6C S100A13
Entrez ID		5531	3476
HPRD ID		03615	02140
Ensembl ID		ENSG00000149923	ENSG00000089289
Uniprot IDs		P60510	P78318
PDB IDs			4IYP
Enriched GO Terms of Interacting Partners?		Regulation Of Interleukin-12 Biosynthetic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor 4 Signaling Pathway Cellular Response To Growth Factor Stimulus Negative Regulation Of Cellular Metabolic Process Response To Growth Factor Toll-like Receptor Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process NIK/NF-kappaB Signaling Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Transcription, DNA-templated Activation Of Innate Immune Response Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Interleukin-12 Production Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Innate Immune Response Membrane Protein Intracellular Domain Proteolysis Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cell Death Regulation Of Catalytic Activity Response To Interleukin-1 Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin Signaling Pathway Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Innate Immune Response Positive Regulation Of Gene Expression Regulation Of Cell Death Regulation Of Cytokine Biosynthetic Process Innate Immune Response Immune System Process Membrane Protein Proteolysis Transcription From RNA Polymerase II Promoter Immune Response	Protein Localization To Microtubule Protein Localization To Cytoskeleton Interleukin-1 Alpha Secretion Dephosphorylation Immune Response Synaptic Growth At Neuromuscular Junction Regulation Of Receptor Activity Regulation Of Signal Transduction Depurination Collateral Sprouting In Absence Of Injury Phosphate-containing Compound Metabolic Process Regulation Of Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Intracellular Signal Transduction Cellular Protein Modification Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Interleukin-1 Secretion Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition DNA Dealkylation Involved In DNA Repair Base-excision Repair, AP Site Formation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Dephosphorylation Neuron Remodeling Mitotic Nuclear Envelope Reassembly Immune System Process Protein Heterotrimerization Nuclear Envelope Reassembly Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Cell Development Cellular Localization Exocytosis Negative Regulation Of Viral Entry Into Host Cell Deoxyribose Phosphate Catabolic Process Cellular Copper Ion Homeostasis Positive Regulation Of Signal Transduction Negative Regulation Of Epithelial To Mesenchymal Transition Cellular Protein Metabolic Process Regulation Of Viral Entry Into Host Cell Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Phosphorylation Regulation Of Viral Release From Host Cell Negative Regulation Of JAK-STAT Cascade
Tagcloud ?		6j acpp canonical carcinogenic cdk5 delineate e2f6 elf1 glands gprc5a hindered ingenuity ionizing ipa map2 mapk12 mapped microarray nab2 persistently perturbed plcg1 radiation runx1 scarcity sema4d stathmin1 surgically undertook
Tagcloud (Difference) ?		6j acpp canonical carcinogenic cdk5 delineate e2f6 elf1 glands gprc5a hindered ingenuity ionizing ipa map2 mapk12 mapped microarray nab2 persistently perturbed plcg1 radiation runx1 scarcity sema4d stathmin1 surgically undertook
Tagcloud (Intersection) ?