PPP4C and PPP4R1

Number of citations of the paper that reports this interaction (PMID 18715871)
21

Data Source:
HPRD (in vitro, in vivo)

		PPP4C	PPP4R1
Gene Name		protein phosphatase 4, catalytic subunit	protein phosphatase 4, regulatory subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Plasma Membrane Protein Phosphatase 4 Complex	Protein Phosphatase 4 Complex
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding	Phosphoprotein Phosphatase Activity Protein Binding Protein Phosphatase Type 4 Regulator Activity
	Biological Process	Regulation Of Double-strand Break Repair Via Homologous Recombination Dephosphorylation NIK/NF-kappaB Signaling	Protein Phosphorylation Signal Transduction Dephosphorylation Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: CCDC6 DHX38 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R4 REL RELA SMEK2 TIPRL TK1 TMSB4X TP53 TRAF6 TRIM28	4 interactors: CEP63 DISC1 HDAC3 PPP4C
Entrez ID		5531	9989
HPRD ID		03615	05366
Ensembl ID		ENSG00000149923	ENSG00000154845
Uniprot IDs		P60510	Q8TF05
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Interleukin-12 Biosynthetic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor 4 Signaling Pathway Cellular Response To Growth Factor Stimulus Negative Regulation Of Cellular Metabolic Process Response To Growth Factor Toll-like Receptor Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process NIK/NF-kappaB Signaling Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Transcription, DNA-templated Activation Of Innate Immune Response Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Interleukin-12 Production Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Innate Immune Response Membrane Protein Intracellular Domain Proteolysis Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cell Death Regulation Of Catalytic Activity Response To Interleukin-1 Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin Signaling Pathway Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Innate Immune Response Positive Regulation Of Gene Expression Regulation Of Cell Death Regulation Of Cytokine Biosynthetic Process Innate Immune Response Immune System Process Membrane Protein Proteolysis Transcription From RNA Polymerase II Promoter Immune Response	Microtubule Cytoskeleton Organization Spindle Assembly Microtubule-based Process Spindle Organization Cytoskeleton Organization Intracellular Signal Transduction Centriole Replication Regulation Of Double-strand Break Repair Via Homologous Recombination Organelle Assembly Signal Transduction Cellular Response To Fluid Shear Stress Mitochondrial Calcium Ion Homeostasis Signaling Regulation Of Synapse Maturation Centriole Assembly Cell Communication Positive Regulation Of TOR Signaling TOR Signaling
Tagcloud ?		6j acpp canonical carcinogenic cdk5 delineate e2f6 elf1 glands gprc5a hindered ingenuity ionizing ipa map2 mapk12 mapped microarray nab2 persistently perturbed plcg1 radiation runx1 scarcity sema4d stathmin1 surgically undertook
Tagcloud (Difference) ?		6j acpp canonical carcinogenic cdk5 delineate e2f6 elf1 glands gprc5a hindered ingenuity ionizing ipa map2 mapk12 mapped microarray nab2 persistently perturbed plcg1 radiation runx1 scarcity sema4d stathmin1 surgically undertook
Tagcloud (Intersection) ?