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TIPRL and PPP6C
Number of citations of the paper that reports this interaction (PMID
16085932
)
43
Data Source:
BioGRID
(pull down, affinity chromatography technology)
TIPRL
PPP6C
Gene Name
TOR signaling pathway regulator
protein phosphatase 6, catalytic subunit
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Intracellular Membrane-bounded Organelle
Cytosol
Molecular Function
Protein Binding
Protein Serine/threonine Phosphatase Activity
Protein Binding
Metal Ion Binding
Biological Process
DNA Damage Checkpoint
Negative Regulation Of Protein Phosphatase Type 2A Activity
G1/S Transition Of Mitotic Cell Cycle
Protein Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
APP
PPP2CB
PPP4C
PPP6C
5 interactors:
IGBP1
NFKBIE
PRKDC
TGFBR1
TIPRL
Entrez ID
261726
5537
HPRD ID
14608
02141
Ensembl ID
ENSG00000143155
ENSG00000119414
Uniprot IDs
O75663
O00743
PDB IDs
Enriched GO Terms of Interacting Partners
?
Dephosphorylation
Phosphate-containing Compound Metabolic Process
Synaptic Growth At Neuromuscular Junction
Cellular Protein Modification Process
Collateral Sprouting In Absence Of Injury
Protein Dephosphorylation
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Cellular Protein Metabolic Process
Neuron Remodeling
Response To Oxidative Stress
Regulation Of Double-strand Break Repair Via Homologous Recombination
Protein Metabolic Process
Cellular Copper Ion Homeostasis
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Dephosphorylation
Cell Activation
Peptidyl-serine Phosphorylation
Regulation Of Dephosphorylation
Negative Regulation Of Protein Phosphatase Type 2A Activity
D-serine Transport
DNA Damage Checkpoint
B Cell Activation
Regulation Of Protein Import Into Nucleus
Regulation Of Protein Phosphatase Type 2A Activity
Apoptotic Process
Regulation Of Protein Localization To Nucleus
Programmed Cell Death
Regulation Of Nucleocytoplasmic Transport
Cell Cycle Process
Cell Death
Death
Cell Cycle Checkpoint
Pro-B Cell Differentiation
Anterior/posterior Pattern Specification
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Protein Dephosphorylation
Regulation Of Intracellular Protein Transport
Cell Fate Commitment
Regulation Of Phosphorylation
Positive Regulation Of Transcription, DNA-templated
Cell Cycle
Immunoglobulin V(D)J Recombination
Parathyroid Gland Development
Negative Regulation Of Phosphoprotein Phosphatase Activity
T Cell Receptor V(D)J Recombination
B Cell Lineage Commitment
Regulation Of Apoptotic Process
Lymphoid Progenitor Cell Differentiation
Positive Regulation Of Macromolecule Biosynthetic Process
Endothelial Cell Activation
Positive Regulation Of Gene Expression
Regulation Of Cell Death
Negative Regulation Of Phosphorylation
Negative Regulation Of Hydrolase Activity
Positive Regulation Of Cellular Biosynthetic Process
Ectopic Germ Cell Programmed Cell Death
Pathway-restricted SMAD Protein Phosphorylation
Lymphocyte Activation
Positive Regulation Of SMAD Protein Import Into Nucleus
Regulation Of Microtubule-based Movement
Regulation Of Intracellular Transport
Negative Regulation Of Cell Cycle
Regulation Of SMAD Protein Import Into Nucleus
Tagcloud
?
actionable
adamts18
col1a1
d816
dgki
epha4
epha7
g12
g13
gna11
gnaq
gucy2c
k642
kalrn
l576
melanomas
mined
ngs
nras
pik3r4
prkaa2
q209
q61
stk31
taf1l
trpm6
v559
v600
w557
Tagcloud (Difference)
?
actionable
adamts18
col1a1
d816
dgki
epha4
epha7
g12
g13
gna11
gnaq
gucy2c
k642
kalrn
l576
melanomas
mined
ngs
nras
pik3r4
prkaa2
q209
q61
stk31
taf1l
trpm6
v559
v600
w557
Tagcloud (Intersection)
?