MYB and ZMYND11

Number of citations of the paper that reports this interaction (PMID 11244510)
12

Data Source:
BioGRID (pull down, two hybrid)

		MYB	ZMYND11
Gene Name		v-myb avian myeloblastosis viral oncogene homolog	zinc finger, MYND-type containing 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Nuclear Matrix	Nucleus Nucleoplasm Chromosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding WD40-repeat Domain Binding	DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Calcium Ion Transport Blood Coagulation B Cell Differentiation Positive Regulation Of T-helper Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development Embryonic Digestive Tract Development Homeostasis Of Number Of Cells Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone H3-K9 Methylation Cellular Response To Interleukin-6	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cell Cycle Cell Proliferation Viral Process Chromatin Modification Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of JNK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Beta thalassemia/hemoglobin E disease ( 20183929) HbA2 levels ( 23043469) Hematocrit ( 19862010) Hematological and biochemical traits ( 20139978) Hematological parameters ( 19820697) Hematology traits ( 23263863 19853236) Mean corpuscular hemoglobin ( 23263863 20139978 19862010) Mean corpuscular hemoglobin concentration ( 23263863 20139978) Mean corpuscular volume ( 23263863 20139978 19862010) Mean platelet volume ( 22423221) Multiple sclerosis ( 21833088) Obesity-related traits ( 23251661) Other erythrocyte phenotypes ( 19862010) Platelet counts ( 22139419 20139978) Red blood cell count ( 20139978) Red blood cell traits ( 20927387) White blood cell count ( 20139978) White blood cell types ( 21738478)
Protein-Protein Interactions		43 interactors: BTRC CCND3 CEBPB CEBPE CHD3 CREBBP CSNK2A1 EP300 ERC2 FBXW2 FBXW5 FBXW7 HIPK2 HLF KAT2A MAF MAPK1 MYBBP1A MYOZ2 NCL NCOR1 NLK PAX5 PIAS1 PML PPM1K RBX1 RPL4 RQCD1 SIN3A SKI SKP2 SMARCA2 SND1 SP100 SUMO1 SUMO2 TRIM28 TTF2 UBE2I UPF2 ZFHX3 ZMYND11	23 interactors: BMPR1A C11orf30 DYNLL1 E2F6 ETS2 EZH1 EZH2 H3F3A HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1
Entrez ID		4602	10771
HPRD ID		01810	09830
Ensembl ID		ENSG00000118513	ENSG00000015171
Uniprot IDs		P10242 Q14025 Q708E1 Q708E9	B7Z2J6 Q15326 Q5BJG6 Q5UGI2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Protein Sumoylation Cellular Protein Modification Process Rhythmic Process Protein Modification By Small Protein Conjugation Developmental Process Peptidyl-lysine Modification PML Body Organization Cell Cycle Regulation Of Signal Transduction Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Metabolic Process RNA Biosynthetic Process Gene Expression Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Nucleobase-containing Compound Metabolic Process Developmental Process Regulation Of Gene Expression, Epigenetic Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Paraxial Mesoderm Morphogenesis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Chromosome Organization Cell Differentiation Nitrogen Compound Metabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Gene Expression, Epigenetic Paraxial Mesoderm Development Transcription From RNA Polymerase II Promoter Chromatin Modification Response To Growth Factor Positive Regulation Of Signal Transduction Immune System Process Cellular Metabolic Process Positive Regulation Of Metabolic Process Multicellular Organismal Development Gene Silencing
Tagcloud ?		amphibian amphibians assume definitive deoxynucleotidyl ectotherms elasmobranchs elegant extraembryonic gata gnathostomes grafting hematopoiesis icm ikaros intraembryonic lck leydig lymphopoiesis mesoderm myeloblastosis oellacher primitive rag spiral tdt teleosts thymopoietic undeniably vertebrates	3k36me3 abrogate astrocytomas base bs69 building childhood chondroblastoma composed consists copies disruption giant h2a h2b h3 h4 importantly missense nucleosome octamer pairs pediatric question raise reader somatic tumorigenesis wrapped
Tagcloud (Difference) ?		amphibian amphibians assume definitive deoxynucleotidyl ectotherms elasmobranchs elegant extraembryonic gata gnathostomes grafting hematopoiesis icm ikaros intraembryonic lck leydig lymphopoiesis mesoderm myeloblastosis oellacher primitive rag spiral tdt teleosts thymopoietic undeniably vertebrates	3k36me3 abrogate astrocytomas base bs69 building childhood chondroblastoma composed consists copies disruption giant h2a h2b h3 h4 importantly missense nucleosome octamer pairs pediatric question raise reader somatic tumorigenesis wrapped
Tagcloud (Intersection) ?