SENP6 and ARNT

Number of citations of the paper that reports this interaction (PMID 12354770)
9

Data Source:
HPRD (in vivo, in vitro)

		SENP6	ARNT
Gene Name		SUMO1/sentrin specific peptidase 6	aryl hydrocarbon receptor nuclear translocator
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	Protein Binding SUMO-specific Protease Activity	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Aryl Hydrocarbon Receptor Activity Protein Binding Transcription Factor Binding Aryl Hydrocarbon Receptor Binding Enhancer Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Proteolysis Protein Sumoylation Protein Desumoylation Protein Modification By Small Protein Removal Regulation Of Spindle Assembly Regulation Of Kinetochore Assembly	Response To Hypoxia Embryonic Placenta Development Positive Regulation Of Endothelial Cell Proliferation Transcription, DNA-templated Positive Regulation Vascular Endothelial Growth Factor Production Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Sumoylation MRNA Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Glycolytic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hormone Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia
Pathways			Cellular response to hypoxia Regulation of Hypoxia-inducible Factor (HIF) by oxygen Regulation of gene expression by Hypoxia-inducible Factor
Drugs
Diseases
GWAS		Height ( 20881960)	Melanoma ( 21983785) Rhegmatogenous retinal detachment ( 23585552) Urate levels ( 23263486)
Protein-Protein Interactions		5 interactors: ARNT PLA2G2A SP1 SUMO1 SUMO2	37 interactors: ADH5 AHR AHRR AIP ARNT2 BRCA1 CSNK2A1 DIABLO EP300 EPAS1 ESR1 GMNN GTF2F1 GTF2F2 HEY1 HEY2 HIF1A IRAK4 LSM8 MTA3 NCOA1 NCOA2 NCOA7 NCOR2 NPAS4 PML PTGES3 SENP6 SIM1 SIM2 SMAD9 SP1 SRC STRBP TNFAIP1 TRIP11 UBE2I
Entrez ID		26054	405
HPRD ID		05417	00524
Ensembl ID		ENSG00000112701	ENSG00000143437
Uniprot IDs		B3KMM0 Q9GZR1	A8K6P0 B0AZM1 F8WAP6 P27540
PDB IDs			1D7G 1X0O 2A24 2ARN 2B02 2HV1 2K7S 3F1N 3F1O 3F1P 3H7W 3H82 4EQ1 4GHI 4GS9 4H6J
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Sequestering Of Nodal From Receptor Via Nodal Binding Embryonic Placenta Development Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Nodal Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Placenta Development Regulation Of Proteasomal Protein Catabolic Process Post-translational Protein Modification PML Body Organization Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Peptidyl-lysine Modification Protein Localization To Nuclear Pore Determination Of Left/right Asymmetry In Lateral Mesoderm Positive Regulation Of Protein Metabolic Process Regulation Of Nodal Signaling Pathway Protein Localization To Nuclear Envelope Regulation Of Epithelial Cell Proliferation Positive Regulation Of Proteolysis Sequestering Of Extracellular Ligand From Receptor Negative Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation By Host Of Viral Transcription Embryonic Process Involved In Female Pregnancy Positive Regulation Of Hormone Biosynthetic Process Low-density Lipoprotein Particle Remodeling Regulation Of Protein Catabolic Process MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Glycolytic Process Positive Regulation Of Protein Sumoylation Lateral Mesoderm Development Phosphatidylinositol Acyl-chain Remodeling Enucleate Erythrocyte Differentiation Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling MRNA Transcription Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Extracellular Negative Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Embryonic Organ Development Reproductive Structure Development Regulation Of Protein Sumoylation Phosphatidylethanolamine Acyl-chain Remodeling Reproductive System Development	Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Rhythmic Process Signal Transduction Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Tube Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Involved In Reproduction Signaling Intracellular Receptor Signaling Pathway Embryonic Placenta Development Cell Communication Reproductive Structure Development Response To Stimulus Negative Regulation Of Biosynthetic Process Reproductive System Development Regulation Of Cellular Process Embryo Development Organ Development Single Organism Reproductive Process Multicellular Organismal Development
Tagcloud ?		attenuator catalyzing conjugated cyld dampening de defense deubiquitinase dynamically endotoxin highlights ikkgamma impairs intriguing mechanistically modifier nemo onto posttranslational potentiated reverses shape strengthening sumo sumoylation tlr tlrs toll	belong bhlh cobalt confers dimerizes frame helix heterodimer heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity pas prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections
Tagcloud (Difference) ?		attenuator catalyzing conjugated cyld dampening de defense deubiquitinase dynamically endotoxin highlights ikkgamma impairs intriguing mechanistically modifier nemo onto posttranslational potentiated reverses shape strengthening sumo sumoylation tlr tlrs toll	belong bhlh cobalt confers dimerizes frame helix heterodimer heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity pas prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections
Tagcloud (Intersection) ?