ARNT and ARNT2

Number of citations of the paper that reports this interaction (PMID 8927054)
29

Data Source:
HPRD (two hybrid)

		ARNT	ARNT2
Gene Name		aryl hydrocarbon receptor nuclear translocator	aryl-hydrocarbon receptor nuclear translocator 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Aryl Hydrocarbon Receptor Activity Protein Binding Transcription Factor Binding Aryl Hydrocarbon Receptor Binding Enhancer Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Signal Transducer Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity
	Biological Process	Response To Hypoxia Embryonic Placenta Development Positive Regulation Of Endothelial Cell Proliferation Transcription, DNA-templated Positive Regulation Vascular Endothelial Growth Factor Production Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Sumoylation MRNA Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Glycolytic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hormone Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia	Response To Hypoxia In Utero Embryonic Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Central Nervous System Development Brain Development Positive Regulation Of Cell Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Cellular response to hypoxia Regulation of Hypoxia-inducible Factor (HIF) by oxygen Regulation of gene expression by Hypoxia-inducible Factor
Drugs
Diseases
GWAS		Melanoma ( 21983785) Rhegmatogenous retinal detachment ( 23585552) Urate levels ( 23263486)
Protein-Protein Interactions		37 interactors: ADH5 AHR AHRR AIP ARNT2 BRCA1 CSNK2A1 DIABLO EP300 EPAS1 ESR1 GMNN GTF2F1 GTF2F2 HEY1 HEY2 HIF1A IRAK4 LSM8 MTA3 NCOA1 NCOA2 NCOA7 NCOR2 NPAS4 PML PTGES3 SENP6 SIM1 SIM2 SMAD9 SP1 SRC STRBP TNFAIP1 TRIP11 UBE2I	59 interactors: ADAMTSL4 APP ARNT BZRAP1 CALCOCO2 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 GOLGA2 HIF1A IKZF3 KIFC3 LZTS2 MAGEA4 MEIS2 MEOX2 MIPOL1 MTUS2 NCOA3 NDE1 NPAS2 NPAS3 NPAS4 PDE4DIP PLSCR1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM2 SORBS3 SPAG5 SSBP3 SSX2IP SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRAF4 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 USHBP1 USP7 VPS52 ZNF341
Entrez ID		405	9915
HPRD ID		00524	06915
Ensembl ID		ENSG00000143437	ENSG00000172379
Uniprot IDs		A8K6P0 B0AZM1 F8WAP6 P27540	Q7Z3A3 Q86TN1 Q9HBZ2
PDB IDs		1D7G 1X0O 2A24 2ARN 2B02 2HV1 2K7S 3F1N 3F1O 3F1P 3H7W 3H82 4EQ1 4GHI 4GS9 4H6J
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Rhythmic Process Signal Transduction Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Tube Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Involved In Reproduction Signaling Intracellular Receptor Signaling Pathway Embryonic Placenta Development Cell Communication Reproductive Structure Development Response To Stimulus Negative Regulation Of Biosynthetic Process Reproductive System Development Regulation Of Cellular Process Embryo Development Organ Development Single Organism Reproductive Process Multicellular Organismal Development	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Microtubule-based Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Localization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Cellular Process Regulation Of Signal Transduction Microtubule Cytoskeleton Organization Regulation Of Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process NIK/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Organ Development Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Embryonic Placenta Development Organelle Organization Positive Regulation Of NF-kappaB Transcription Factor Activity Spindle Organization Microtubule-based Transport Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Protein Homodimerization Activity Cytoskeleton-dependent Intracellular Transport Regulation Of DNA-templated Transcription In Response To Stress
Tagcloud ?		belong bhlh cobalt confers dimerizes frame helix heterodimer heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity pas prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections	adenovirus ahr arises aromatic aryl bhlh cbp conveys dioxin e1a extensively gst heterodimer hlf hybrid hydrocarbon hydrocarbons interacted metabolizing methylcholanthrene partner pas pull sim somehow tetrachlorodibenzo transactivation translocator
Tagcloud (Difference) ?		belong cobalt confers dimerizes frame helix heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections	adenovirus ahr arises aromatic aryl cbp conveys dioxin e1a extensively gst hlf hybrid hydrocarbon hydrocarbons interacted metabolizing methylcholanthrene partner pull sim somehow tetrachlorodibenzo transactivation translocator
Tagcloud (Intersection) ?		bhlh heterodimer pas