ARNT and AHRR

Number of citations of the paper that reports this interaction (PMID 9887096)
54

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		ARNT	AHRR
Gene Name		aryl hydrocarbon receptor nuclear translocator	aryl-hydrocarbon receptor repressor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex	Cytoplasm Nuclear Aryl Hydrocarbon Receptor Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Aryl Hydrocarbon Receptor Activity Protein Binding Transcription Factor Binding Aryl Hydrocarbon Receptor Binding Enhancer Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Signal Transducer Activity Protein Dimerization Activity
	Biological Process	Response To Hypoxia Embryonic Placenta Development Positive Regulation Of Endothelial Cell Proliferation Transcription, DNA-templated Positive Regulation Vascular Endothelial Growth Factor Production Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Sumoylation MRNA Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Glycolytic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hormone Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Signal Transduction Response To Xenobiotic Stimulus Positive Regulation Of Protein Sumoylation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Cellular response to hypoxia Regulation of Hypoxia-inducible Factor (HIF) by oxygen Regulation of gene expression by Hypoxia-inducible Factor
Drugs
Diseases
GWAS		Melanoma ( 21983785) Rhegmatogenous retinal detachment ( 23585552) Urate levels ( 23263486)	Cystic fibrosis severity ( 21602797) Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		37 interactors: ADH5 AHR AHRR AIP ARNT2 BRCA1 CSNK2A1 DIABLO EP300 EPAS1 ESR1 GMNN GTF2F1 GTF2F2 HEY1 HEY2 HIF1A IRAK4 LSM8 MTA3 NCOA1 NCOA2 NCOA7 NCOR2 NPAS4 PML PTGES3 SENP6 SIM1 SIM2 SMAD9 SP1 SRC STRBP TNFAIP1 TRIP11 UBE2I	1 interactors: ARNT
Entrez ID		405	57491
HPRD ID		00524	07356
Ensembl ID		ENSG00000143437	ENSG00000063438
Uniprot IDs		A8K6P0 B0AZM1 F8WAP6 P27540	A9YTQ3
PDB IDs		1D7G 1X0O 2A24 2ARN 2B02 2HV1 2K7S 3F1N 3F1O 3F1P 3H7W 3H82 4EQ1 4GHI 4GS9 4H6J
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Rhythmic Process Signal Transduction Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Tube Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Involved In Reproduction Signaling Intracellular Receptor Signaling Pathway Embryonic Placenta Development Cell Communication Reproductive Structure Development Response To Stimulus Negative Regulation Of Biosynthetic Process Reproductive System Development Regulation Of Cellular Process Embryo Development Organ Development Single Organism Reproductive Process Multicellular Organismal Development	Positive Regulation Of Hormone Biosynthetic Process MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Glycolytic Process Positive Regulation Of Protein Sumoylation MRNA Transcription Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Protein Sumoylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Hormone Biosynthetic Process Regulation Of Glycolytic Process Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Vascular Endothelial Growth Factor Production Regulation Of Hormone Metabolic Process Regulation Of Erythrocyte Differentiation Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Endothelial Cell Proliferation Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Myeloid Cell Differentiation Regulation Of Endothelial Cell Proliferation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Embryonic Placenta Development Positive Regulation Of Epithelial Cell Proliferation Regulation Of Carbohydrate Metabolic Process Regulation Of Myeloid Cell Differentiation Regulation Of Cellular Response To Growth Factor Stimulus Placenta Development Intracellular Receptor Signaling Pathway Cellular Response To Oxidative Stress Regulation Of Epithelial Cell Proliferation Response To Hypoxia Positive Regulation Of Cytokine Production
Tagcloud ?		belong bhlh cobalt confers dimerizes frame helix heterodimer heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity pas prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections	125b abrogated aryl augmenting bioinformatic bona cisplatin consistently enabled fide hydrocarbon integrative messenger micrornas mimic mir mir125b1 mirna mirnas nrf2 oltipraz protecting repressor serves transactivated transcriptionally uncharacterized verified
Tagcloud (Difference) ?		belong bhlh cobalt confers dimerizes frame helix heterodimer heterodimeric heterologous hif1alpha hif2alpha hif3alpha hifs hrd1 hre hypoxia identity pas prototype reading recognizes resultant shares superfamily tacgtg tension thymus transfections	125b abrogated aryl augmenting bioinformatic bona cisplatin consistently enabled fide hydrocarbon integrative messenger micrornas mimic mir mir125b1 mirna mirnas nrf2 oltipraz protecting repressor serves transactivated transcriptionally uncharacterized verified
Tagcloud (Intersection) ?