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PTPN23 and CEP55
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
PTPN23
CEP55
Description
protein tyrosine phosphatase non-receptor type 23
centrosomal protein 55
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Cytosol
Cytoskeleton
Cilium
Nuclear Body
Cytoplasmic Vesicle
Centriolar Satellite
Ciliary Basal Body
Cell Projection
Extracellular Exosome
Cytoplasm
Centrosome
Centriole
Cytoskeleton
Membrane
Midbody
Cleavage Furrow
Intercellular Bridge
Flemming Body
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Hydrolase Activity
Protein Kinase Binding
Protein Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Epithelial Cell Migration
Protein Transport
Cell Projection Organization
Endocytic Recycling
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Early Endosome To Late Endosome Transport
Cilium Assembly
Positive Regulation Of Wnt Protein Secretion
Positive Regulation Of Homophilic Cell Adhesion
Positive Regulation Of Adherens Junction Organization
Positive Regulation Of Early Endosome To Late Endosome Transport
Mitotic Cytokinesis
Nucleus Organization
Mitotic Metaphase Chromosome Alignment
Establishment Of Protein Localization
Cell Division
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Midbody Abscission
Cranial Skeletal System Development
Pathways
Interleukin-37 signaling
Drugs
Diseases
GWAS
C-reactive protein levels (
30388399
)
Refractive error (
32231278
)
Type 2 diabetes (adjusted for BMI) (
29632382
)
High density lipoprotein cholesterol levels (
30498476
)
Metabolite levels (
23823483
)
Interacting Genes
12 interacting genes:
ALG2
BICD1
CEP19
CEP55
CHMP4B
DDX24
LRRK2
NOTCH2NLA
PSMA3
TRIM27
UBAP1
WDR4
94 interacting genes:
AIRIM
AKAP9
ANXA11
ARHGEF15
BAG4
C1orf216
CBY2
CCBE1
CCDC120
CCHCR1
CDC37
CDC45
CDK1
CDSN
CEP57L1
CFTR
COL8A1
CPSF7
DTNB
ECSIT
EIF1AD
ENKD1
ESS2
EXOSC5
FAM161B
FAM90A1
FBF1
FXR2
GOLGA2
GOLGA8DP
HAUS1
HGS
HNRNPA0
HSF2BP
KANK2
KIFC3
KRT31
LENG1
LGALS4
LRRC23
MAPK1
MAPK1IP1L
MFAP1
MIA3
MORF4L2
NDEL1
NEDD4L
NOS3
NTAQ1
NXF1
OGT
PCNT
PDCD6IP
PEF1
PIN1
PLEKHG6
PLK1
POLM
POM121
PPP1R16B
PRPF6
PSEN2
PSMC2
PTPN23
PWWP3A
RAB3D
RBM14
RBM17
RBM22
RBM42
RBPMS
RCOR3
RNF32
SDCBP
SF1
SFPQ
SNRPB
SNRPN
SNW1
SS18L1
SUPT5H
TCL1A
TEAD4
TEX11
TFG
TFIP11
TP53BP2
TSG101
UBC
VPS37C
VPS37D
WASHC1
WASHC3
ZNF48
Entrez ID
25930
55165
HPRD ID
05959
12569
Ensembl ID
ENSG00000076201
ENSG00000138180
Uniprot IDs
B4DST5
Q9H3S7
Q53EZ4
PDB IDs
3RAU
5CRU
5CRV
5LM1
5LM2
5MJY
5MJZ
5MK0
5MK1
5MK2
5MK3
3E1R
3WUT
3WUU
3WUV
Enriched GO Terms of Interacting Partners
?
Organelle Localization
Microtubule Anchoring
Microtubule Anchoring At Microtubule Organizing Center
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Multivesicular Body Assembly
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Multivesicular Body Organization
Mitotic Cytokinetic Process
Midbody Abscission
Late Endosome To Vacuole Transport
Vesicle-mediated Transport
Intracellular Transport
Endosomal Transport
Membrane Organization
Endosome Transport Via Multivesicular Body Sorting Pathway
Membrane Fission
Multivesicular Body Sorting Pathway
Metaphase Chromosome Alignment
Cytokinetic Process
Mitotic Metaphase Chromosome Alignment
Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
GDP-Man:Man(1)GlcNAc(2)-PP-Dol Alpha-1,3-mannosyltransferase Activity
GDP-Man:Man(2)GlcNAc(2)-PP-Dol Alpha-1,6-mannosyltransferase Activity
Cellular Response To Curcumin
Caveola Neck
GTP-dependent Protein Kinase Activity
Wnt Signalosome Assembly
Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Organelle Assembly
Endosome
TRNA Methyltransferase Activator Activity
TRNA (m7G46) Methyltransferase Complex
Mitotic Cytokinesis
Chromosome Localization
Alpha-1,3-mannosyltransferase Activity
Negative Regulation Of Late Endosome To Lysosome Transport
Amphisome
Peroxidase Inhibitor Activity
Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion
Beta-catenin Destruction Complex Binding
Endosome Organization
Establishment Of Protein Localization To Organelle
Proteinase Activated Receptor Binding
Negative Regulation Of Catabolic Process
TRNA (guanine-N7)-methylation
Cytoskeleton-dependent Cytokinesis
Nucleus Organization
Regulation Of Notch Signaling Pathway
Positive Regulation Of Protein Autoubiquitination
Response To Curcumin
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Protein Binding
Spliceosomal Complex
Centrosome
MRNA Processing
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
RNA Splicing
Nucleoplasm
MRNA Metabolic Process
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Catalytic Step 2 Spliceosome
Cytoskeleton
Multivesicular Body Assembly
Multivesicular Body Organization
Positive Regulation Of Exosomal Secretion
Late Endosome To Vacuole Transport
Organelle Organization
Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Endosome Transport Via Multivesicular Body Sorting Pathway
RNA Processing
Calcium-dependent Protein Binding
RNA Binding
Viral Budding Via Host ESCRT Complex
Multivesicular Body Sorting Pathway
Positive Regulation Of Exocytosis
Viral Budding
MRNA Binding
Protein Localization To Vacuole
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Cellular Component Assembly
Nucleic Acid Metabolic Process
Microtubule Nucleation
Cytosol
Establishment Of Protein Localization To Vacuole
ESCRT I Complex
Centriole
Cytoplasm
Spindle
Nucleic Acid Binding
U4/U6 X U5 Tri-snRNP Complex
Microtubule Cytoskeleton Organization Involved In Mitosis
MRNA Cis Splicing, Via Spliceosome
SnRNP Binding
Endosome Organization
Microtubule Organizing Center Organization
Membrane Fission
Microtubule-based Process
Organelle Assembly
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Tagcloud (Intersection)
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