PTPN23 and DDX24

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PTPN23	DDX24
Description		protein tyrosine phosphatase non-receptor type 23	DEAD-box helicase 24
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Cytoskeleton Cilium Nuclear Body Cytoplasmic Vesicle Centriolar Satellite Ciliary Basal Body Cell Projection Extracellular Exosome	Nucleus Nucleolus Cytoplasm Membrane
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Protein Kinase Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Negative Regulation Of Epithelial Cell Migration Protein Transport Cell Projection Organization Endocytic Recycling Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Early Endosome To Late Endosome Transport Cilium Assembly Positive Regulation Of Wnt Protein Secretion Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport	RNA Metabolic Process
Pathways		Interleukin-37 signaling
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Refractive error ( 32231278) Type 2 diabetes (adjusted for BMI) ( 29632382)	Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		12 interacting genes: ALG2 BICD1 CEP19 CEP55 CHMP4B DDX24 LRRK2 NOTCH2NLA PSMA3 TRIM27 UBAP1 WDR4	37 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD FILNC1 GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTEN PTPN23 RAE1 RNF10 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I USP7 VDAC3
Entrez ID		25930	57062
HPRD ID		05959	05860
Ensembl ID		ENSG00000076201	ENSG00000089737
Uniprot IDs		B4DST5 Q9H3S7	Q9GZR7
PDB IDs		3RAU 5CRU 5CRV 5LM1 5LM2 5MJY 5MJZ 5MK0 5MK1 5MK2 5MK3
Enriched GO Terms of Interacting Partners?		Organelle Localization Microtubule Anchoring Microtubule Anchoring At Microtubule Organizing Center Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Organization Mitotic Cytokinetic Process Midbody Abscission Late Endosome To Vacuole Transport Vesicle-mediated Transport Intracellular Transport Endosomal Transport Membrane Organization Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway Metaphase Chromosome Alignment Cytokinetic Process Mitotic Metaphase Chromosome Alignment Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment GDP-Man:Man(1)GlcNAc(2)-PP-Dol Alpha-1,3-mannosyltransferase Activity GDP-Man:Man(2)GlcNAc(2)-PP-Dol Alpha-1,6-mannosyltransferase Activity Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Organelle Assembly Endosome TRNA Methyltransferase Activator Activity TRNA (m7G46) Methyltransferase Complex Mitotic Cytokinesis Chromosome Localization Alpha-1,3-mannosyltransferase Activity Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Beta-catenin Destruction Complex Binding Endosome Organization Establishment Of Protein Localization To Organelle Proteinase Activated Receptor Binding Negative Regulation Of Catabolic Process TRNA (guanine-N7)-methylation Cytoskeleton-dependent Cytokinesis Nucleus Organization Regulation Of Notch Signaling Pathway Positive Regulation Of Protein Autoubiquitination Response To Curcumin	RNA-templated DNA Biosynthetic Process Shelterin Complex Cellular Component Assembly Nuclear Body Regulation Of Protein Stability Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Negative Regulation Of Cellular Component Organization Telomere Capping Regulation Of Cellular Component Organization PML Body Regulation Of Telomere Maintenance Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Organelle Organization Protein Localization To Organelle Negative Regulation Of Macromolecule Metabolic Process Protein Stabilization Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Catabolic Process Telomere Maintenance Via Telomerase P53 Binding Regulation Of Cell Cycle Process Negative Regulation Of Metabolic Process Regulation Of Cell Communication Protein-containing Complex Regulation Of Signaling Regulation Of Organelle Organization Telomeric DNA Binding Negative Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Telomere Maintenance Via Telomere Lengthening DNA Biosynthetic Process Nucleoplasm Regulation Of Cell Cycle Telomere Maintenance Receptor Serine/threonine Kinase Binding Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Apoptotic Process Negative Regulation Of Telomere Maintenance Regulation Of DNA Metabolic Process Establishment Of Protein Localization To Organelle Positive Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Activity Protection From Non-homologous End Joining At Telomere Negative Regulation Of Small Molecule Metabolic Process
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