PTPN23 and DDX24

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PTPN23	DDX24
Gene Name		protein tyrosine phosphatase, non-receptor type 23	DEAD (Asp-Glu-Ala-Asp) box helicase 24
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytoplasmic Membrane-bounded Vesicle Ciliary Basal Body Extracellular Vesicular Exosome	Nucleolus Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding	RNA Helicase Activity ATP Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Epithelial Cell Migration Protein Transport Peptidyl-tyrosine Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cilium Morphogenesis Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport	RNA Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ALG2 CEP55 CHMP4B DDX24 GRB2 LRRK2 NOTCH2NL PSMA3 TRIM27	31 interactors: BCS1L BRCA1 C9orf9 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTPN23 RAE1 SPTAN1 SUMO1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 VDAC3
Entrez ID		25930	57062
HPRD ID		05959	05860
Ensembl ID		ENSG00000076201	ENSG00000089737
Uniprot IDs		B4DST5 Q9H3S7	G3V529 Q4V9L5 Q9GZR7
PDB IDs		3RAU
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Regulation Of Viral Release From Host Cell Positive Regulation Of Proteolysis Regulation Of Protein Complex Assembly Regulation Of Organelle Organization Protein Localization Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Thioredoxin Peroxidase Activity By Peptidyl-threonine Phosphorylation Protein Glycosylation In Endoplasmic Reticulum Negative Regulation Of Peroxidase Activity Negative Regulation Of Signal Transduction Protein Oligomerization Signal Transduction In Response To DNA Damage Negative Regulation Of Signaling Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Regulation Of Autophagy Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of Protein Autoubiquitination Positive Regulation Of Protein Polymerization Viral Process Cellular Response To Dopamine Negative Regulation Of Autophagic Vacuole Assembly Regulation Of Protein Autoubiquitination Positive Regulation Of Dopamine Receptor Signaling Pathway Maintenance Of Lens Transparency Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Protein Targeting To Mitochondrion Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Kidney Size Regulation Of Viral Process Cellular Response To Stress Regulation Of Proteolysis Mitotic Cell Cycle Process Regulation Of Cell Death Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Cellular Response To Manganese Ion Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Transport Negative Regulation Of Calcium Ion Import Intracellular Distribution Of Mitochondria	Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Maintenance RNA-dependent DNA Replication Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Regulation Of Organelle Organization Telomere Capping DNA Replication Protein Localization To Chromosome, Telomeric Region Cell Cycle Regulation Of Cell Cycle Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Replicative Cell Aging Response To Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Component Organization Cellular Response To Cytokine Stimulus Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Apoptotic Process Mitotic Cell Cycle Process Programmed Cell Death Regulation Of Protein Metabolic Process Response To Cytokine Organelle Organization Cell Cycle Process DNA Metabolic Process Cell Death Death Regulation Of Cytokine-mediated Signaling Pathway Response To External Stimulus Negative Regulation Of DNA Metabolic Process Developmental Process Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Signal Transduction
Tagcloud ?			abrogation box consequent consistently dead degradation elicit helicase interacts mdm2 mediates networks nonproteolytic nucleolar polyubiquitylation pre preribosomal processing promoted proteasomal ribonucleoprotein rrna rrnp stabilization steps triggers ubiquitylation unexpected unexpectedly
Tagcloud (Difference) ?			abrogation box consequent consistently dead degradation elicit helicase interacts mdm2 mediates networks nonproteolytic nucleolar polyubiquitylation pre preribosomal processing promoted proteasomal ribonucleoprotein rrna rrnp stabilization steps triggers ubiquitylation unexpected unexpectedly
Tagcloud (Intersection) ?