PTPN23

Gene Name		protein tyrosine phosphatase, non-receptor type 23
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytoplasmic Membrane-bounded Vesicle Ciliary Basal Body Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Epithelial Cell Migration Protein Transport Peptidyl-tyrosine Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cilium Morphogenesis Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: ALG2 CEP55 CHMP4B DDX24 GRB2 LRRK2 NOTCH2NL PSMA3 TRIM27
Entrez ID		25930
HPRD ID		05959
Ensembl ID		ENSG00000076201
Uniprot IDs		B4DST5 Q9H3S7
PDB IDs		3RAU
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Regulation Of Viral Release From Host Cell Positive Regulation Of Proteolysis Regulation Of Protein Complex Assembly Regulation Of Organelle Organization Protein Localization Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Thioredoxin Peroxidase Activity By Peptidyl-threonine Phosphorylation Protein Glycosylation In Endoplasmic Reticulum Negative Regulation Of Peroxidase Activity Negative Regulation Of Signal Transduction Protein Oligomerization Signal Transduction In Response To DNA Damage Negative Regulation Of Signaling Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Regulation Of Autophagy Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of Protein Autoubiquitination Positive Regulation Of Protein Polymerization Viral Process Cellular Response To Dopamine Negative Regulation Of Autophagic Vacuole Assembly Regulation Of Protein Autoubiquitination Positive Regulation Of Dopamine Receptor Signaling Pathway Maintenance Of Lens Transparency Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Protein Targeting To Mitochondrion Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Kidney Size Regulation Of Viral Process Cellular Response To Stress Regulation Of Proteolysis Mitotic Cell Cycle Process Regulation Of Cell Death Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Cellular Response To Manganese Ion Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Transport Negative Regulation Of Calcium Ion Import Intracellular Distribution Of Mitochondria
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