THUMPD3 and LSM8

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		THUMPD3	LSM8
Gene Name		THUMP domain containing 3	LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm	Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	RNA Binding Methyltransferase Activity	Protein Binding U6 SnRNA Binding U6 SnRNA 3'-end Binding Poly(A) RNA Binding
	Biological Process	Methylation	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: LSM8	49 interactors: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FAM63A FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MGA MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPT10 SEPT5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		25917	51691
HPRD ID		15507	06288
Ensembl ID		ENSG00000134077
Uniprot IDs		Q9BV44	A4D0W0 O95777
PDB IDs
Enriched GO Terms of Interacting Partners?			Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nucleobase-containing Compound Metabolic Process Aromatic Compound Catabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Processing RNA Processing Catabolic Process Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Catabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cellular Metabolic Process Histone MRNA Metabolic Process Pentose Biosynthetic Process Metabolic Process Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Spliceosomal Complex Assembly Dosage Compensation Ribonucleoprotein Complex Assembly Ribosome Biogenesis Pentose-phosphate Shunt Glyceraldehyde-3-phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Glucose 6-phosphate Metabolic Process RRNA Processing NcRNA Metabolic Process Starch Catabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Response To Type III Interferon Dolichol Biosynthetic Process NADP Metabolic Process RRNA Metabolic Process Spliceosomal SnRNP Assembly Carbohydrate Biosynthetic Process D-gluconate Metabolic Process Response To Vitamin B2
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