SCMH1 and PHC1

Number of citations of the paper that reports this interaction (PMID 22325352)
61

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SCMH1	PHC1
Gene Name		sex comb on midleg homolog 1 (Drosophila)	polyhomeotic homolog 1 (Drosophila)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromocenter	Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	DNA Binding Chromatin Binding Zinc Ion Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Spermatogenesis Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Gene Silencing Negative Regulation Of Transcription, DNA-templated	Multicellular Organismal Development Histone Ubiquitination Cellular Response To Retinoic Acid
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Height ( 20881960 23563607 18391952)
Protein-Protein Interactions		16 interactors: EWSR1 GMNN HK1 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M TMEM11 TOB1 UBQLN1 UBQLN4	18 interactors: BMI1 GMNN HSPA8 PCGF2 PHC2 PIAS2 PPP1CA PPP1CC RING1 RNF2 SCMH1 SFMBT1 SIAH1 SP100 SUMO1 SUMO1P1 UBE2I ZCCHC7
Entrez ID		22955	1911
HPRD ID		11540	16009
Ensembl ID		ENSG00000010803	ENSG00000111752
Uniprot IDs		B3KMZ7 Q96GD3	B4DF21 J3KQH6 P78364 Q6GMQ3 Q6N083
PDB IDs		2P0K	2L8E
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Metabolic Process Chromatin Modification Chromatin Organization Regulation Of Metabolic Process Anterior/posterior Pattern Specification Peptidyl-lysine Modification Protein Sumoylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Ubiquitination Histone Ubiquitination Regulation Of RNA Metabolic Process Chromosome Organization Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Anatomical Structure Morphogenesis Cellular Protein Modification Process Pattern Specification Process Cellular Protein Metabolic Process Developmental Process Regulation Of Signal Transduction Histone H2A Monoubiquitination Histone H2A Ubiquitination Regulation Of Signaling Organelle Organization RNA Metabolic Process Histone Monoubiquitination Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Histone Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Protein Metabolic Process Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Cell Division Cell Cycle Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process
Tagcloud ?		admixture africans await breed ce compositionally deflate eda2r edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs slc24a5 sliding visualise	bmi1a bmi1b cbx2 cbx4 cbx6a cbx6b cbx7a cbx7b cbx8a cbx8b combs enormous orthologs pcgf1 pcgf5a pcgf5b pcgf6 phc2a phc2b phc3 polyhomeotic prc1 psc ring1 rnf2 sce syntenies syntheses trimethylates
Tagcloud (Difference) ?		admixture africans await breed ce compositionally deflate eda2r edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs slc24a5 sliding visualise	bmi1a bmi1b cbx2 cbx4 cbx6a cbx6b cbx7a cbx7b cbx8a cbx8b combs enormous orthologs pcgf1 pcgf5a pcgf5b pcgf6 phc2a phc2b phc3 polyhomeotic prc1 psc ring1 rnf2 sce syntenies syntheses trimethylates
Tagcloud (Intersection) ?