SCMH1 and PHC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		SCMH1	PHC2
Gene Name		sex comb on midleg homolog 1 (Drosophila)	polyhomeotic homolog 2 (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromocenter	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Spermatogenesis Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Gene Silencing Negative Regulation Of Transcription, DNA-templated	Multicellular Organismal Development Spermatogenesis
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Height ( 20881960 23563607 18391952)
Protein-Protein Interactions		16 interactors: EWSR1 GMNN HK1 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M TMEM11 TOB1 UBQLN1 UBQLN4	68 interactors: AEN AFG3L2 AP1M1 BMI1 BSDC1 BYSL C1orf109 CARD9 CBX8 CRKL CSNK2B DRG1 ENKD1 FAM124A FAM13C FAM161A FAM74A1 FAM74A4 FHL3 GFI1B GRB2 HIST3H3 KAT5 KBTBD7 KDM1A KIFC3 L3MBTL3 LMO1 LMO2 LMO3 MAB21L3 MAGEB6 MAPK14 MAPK6 MAPKAPK2 MCM2 MCRS1 MFAP1 MORF4L2 NCK1 PCGF2 PCGF3 PCGF5 PHC1 PLK1 POLR2L PPP1R16B PRKAA1 PRPF31 RBM39 RPL7 RWDD2B SCMH1 SDCBP SFMBT1 SIAH1 SMAD3 SPATC1L SSX2IP SYT16 TAB1 THAP7 TMEM70 TRIM41 ZBTB24 ZGPAT ZMAT2 ZNF417
Entrez ID		22955	1912
HPRD ID		11540	10340
Ensembl ID		ENSG00000010803	ENSG00000134686
Uniprot IDs		B3KMZ7 Q96GD3	B3KPJ4 Q8IXK0
PDB IDs		2P0K
Enriched GO Terms of Interacting Partners?			RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Chromatin Organization Chromosome Organization Chromatin Modification Organelle Organization Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Phosphorylation Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Cellular Response To Stress Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Histone Modification Cellular Response To DNA Damage Stimulus Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Developmental Process Positive Regulation Of Signal Transduction Immune System Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Signal Transduction Anatomical Structure Development Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Immune System Development Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Signal Transduction
Tagcloud ?		admixture africans await breed ce compositionally deflate eda2r edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs slc24a5 sliding visualise	ansa arene bent binuclear bp86 c6 cf3 chelate concurred conversions coordinative diphenylethane ga gaga gallium h5 hexamethylbenzene me2 me3 me6 mesitylene multinuclear olefinic ph2 polyisobutylene reactivities terphenyl univalent xylene
Tagcloud (Difference) ?		admixture africans await breed ce compositionally deflate eda2r edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs slc24a5 sliding visualise	ansa arene bent binuclear bp86 c6 cf3 chelate concurred conversions coordinative diphenylethane ga gaga gallium h5 hexamethylbenzene me2 me3 me6 mesitylene multinuclear olefinic ph2 polyisobutylene reactivities terphenyl univalent xylene
Tagcloud (Intersection) ?