SCMH1 and HK1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		SCMH1	HK1
Gene Name		sex comb on midleg homolog 1 (Drosophila)	hexokinase 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromocenter	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Raft Sperm Principal Piece
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	Glucokinase Activity Hexokinase Activity Protein Binding ATP Binding Fructokinase Activity Mannokinase Activity
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Spermatogenesis Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Gene Silencing Negative Regulation Of Transcription, DNA-templated	Cellular Glucose Homeostasis Carbohydrate Metabolic Process Glycolytic Process Hexose Transport Pathogenesis Glucose Transport Hexose Metabolic Process Small Molecule Metabolic Process Carbohydrate Phosphorylation Glucose 6-phosphate Metabolic Process Transmembrane Transport
Pathways			Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates Glucose transport SLC-mediated transmembrane transport Hexose transport
Drugs			Alpha-D-Glucose-6-Phosphate Beta-D-Glucose Adenosine-5\'-Diphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Height ( 20881960 23563607 18391952)	Glycated hemoglobin levels ( 20858683 19096518) Hematocrit ( 19862010) Hemoglobin ( 19862010) Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978) Red blood cell count ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		16 interactors: EWSR1 GMNN HK1 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M TMEM11 TOB1 UBQLN1 UBQLN4	5 interactors: APP ENO2 SCMH1 VDAC1 VDAC2
Entrez ID		22955	3098
HPRD ID		11540	00809
Ensembl ID		ENSG00000010803	ENSG00000156515
Uniprot IDs		B3KMZ7 Q96GD3	A8K7J7 B3KXY9 P19367 P78542 Q59FD4
PDB IDs		2P0K	1CZA 1DGK 1HKB 1HKC 1QHA 4F9O 4FOE 4FOI 4FPA 4FPB
Enriched GO Terms of Interacting Partners?			Learning Regulation Of Anion Transport Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Learning Or Memory Axon Choice Point Recognition Cognition
Tagcloud ?		admixture africans await breed ce compositionally deflate eda2r edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs slc24a5 sliding visualise	cerebellar cerebellum cerebrum changing demonstration detail e14 exception gestational hexokinase hk3 immunoreactivity infiltration isoforms isozymes layers ontogeny organs p45 phosphorylate postnatally prominent purkinje share speculate spleen track vi
Tagcloud (Difference) ?		admixture africans await breed ce compositionally deflate eda2r edar fst gujarati hemizygous herc2 homozygosity initio lct maasai mathematically organised phylogeography pigmentation prioritised proxy relatedness remodeler runs slc24a5 sliding visualise	cerebellar cerebellum cerebrum changing demonstration detail e14 exception gestational hexokinase hk3 immunoreactivity infiltration isoforms isozymes layers ontogeny organs p45 phosphorylate postnatally prominent purkinje share speculate spleen track vi
Tagcloud (Intersection) ?